The Efficacy of Transcorneal Electrical Stimulation for the Treatment of Primary Open-angle Glaucoma: A Pilot Study.

The Efficacy of Transcorneal Electrical Stimulation for the Treatment of Primary Open-angle Glaucoma: A Pilot Study. Keio J Med. 2018 Feb 07;: Authors: Ota Y, Ozeki N, Yuki K, Shiba D, Kimura I, Tsunoda K, Shinoda K, Ohde H, Tsubota K Abstract The aim of this study was to evaluate the effects of transcorneal electrical stimulation in subjects with primary open-angle glaucoma. Five eyes of four male subjects with primary open-angle glaucoma (average age: 52.25 ± 14.68 years) were enrolled. The subjects underwent transcorneal electrical stimulation every 3 months according to the following procedure. A Dawson-Trick-Litzkow electrode was placed on the cornea, and biphasic electric current pulses (10 ms, 20 Hz) were delivered using a stimulator (BPG-1,BAK Electronics) and a stimulus isolation unit (BSI-2). A current that evoked a phosphene that the subject perceived in the whole visual area was delivered continuously for 30 min. Humphrey visual field testing was performed after every third transcorneal electrical stimulation treatment. Changes in mean deviation (MD) values were evaluated with a linear regression model. Transcorneal electrical stimulation was performed 18.2 ± 9.4 times over a period of 49.8 ± 23.0 months. The average pretranscorneal electrical stimulation intraocular pressure, best corrected visual acuity, and MD values were 11.8 ± 1.79 mmHg, 0.14 ± 0.19 (logMAR) and -17.28 ± 6.24 dB, respective...
Source: The Keio Journal of Medicine - Category: Universities & Medical Training Authors: Tags: Keio J Med Source Type: research

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CONCLUSION: Inpatient consultations is very useful to the patient and managing physician. Although a better knowledge in the identification of common ophthalmic conditions can help to reduce the number of inpatient consults from other medical specialties. PMID: 32476114 [PubMed - in process]
Source: Pain Physician - Category: Anesthesiology Authors: Tags: West Afr J Med Source Type: research
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Source: Molecular Vision - Category: Molecular Biology Tags: Mol Vis Source Type: research
Conditions:   Glaucoma;   OHT - Ocular Hypertension Interventions:   Drug: Timolol 0.5% ophthalmic solution;   Drug: Latanoprost 0.005% Ophthalmic Solution Sponsors:   Ohio State University;   University of Nebraska;   Mayo Clinic Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: September 2020Source: Journal of Trace Elements in Medicine and Biology, Volume 61Author(s): Beatrice Bocca, Giovanni Forte, Andrea Pisano, Cristiano Farace, Ermete Giancipoli, Antonio Pinna, Stefano Dore, Roberto Madeddu
Source: Journal of Trace Elements in Medicine and Biology - Category: Biochemistry Source Type: research
Does anyone have any strong opinions on using either Topcon (Maestro 2 being the newest model) vs. Zeiss Cirrus (6000 being the latest model) as a tool for OCT RNFL/GC analysis and monitoring for progression? The Maestro has the convenient feature of a fundus camera built in. I'm curious if anyone has been happy with their Topcon as a tool in their management of glaucoma and specifically if there are any advantages or disadvantages compared to Cirrus.
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Ophthalmology: Eye Physicians & Surgeons Source Type: forums
Electrical stimulation (ES) by peripheral (transpalpebral/transorbital/transcorneal) approach seems to currently be one of the most promising rehabilitative techniques, which are aimed at the restoration of the visual function in low vision (LV) patients affected by degenerative diseases. The non-invasiveness of this methodology and its many positive effects on multiple retinal cell targets have led to the use of ES in patients with ischemic optic neuritis, traumatic optic nerve lesions, retinitis pigmentosa (RP), cone-rod dystrophy, Best disease, Stargardt disease, retinal vascular occlusions, glaucoma, and dry and wet ag...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - Category: Neurology Authors: Source Type: research
AbstractObjectiveThis prospective study aimed to compare the surgical outcomes of ab externo 240-degree trabeculotomy and trabeculotomy –trabeculectomy in managing primary congenital glaucoma (PCG).Patients and methodsThe study included 30 eyes of 30 patients aged less than 3 years who were diagnosed with PCG and was conducted in Menofia University Hospital between November 2018 and January 2020. The studied eyes were divided into two equal groups. Ab externo 240-degree trabeculotomy and combined trabeculotomy with trabeculectomy with MMC were performed for groups I and II, respectively. Post-operative measurements i...
Source: International Ophthalmology - Category: Opthalmology Source Type: research
CONCLUSION AND IMPORTANCE: We present the second published case worldwide about anterior uveitis secondary to intracameral moxifloxacin, which may rarely cause hypertensive uveitis that may be confused with viral uveitis. This provides evidence on the importance of postoperative follow-up by the surgeon for an early referral and treatment of these cases. PMID: 32469689 [PubMed - as supplied by publisher]
Source: Ocular Immunology and Inflammation - Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research
Abstract A soft coral-derived fungus Penicillium sp. among other isolates e high antibacterial, anti-yeast and cytotoxic activities. The fungus, Penicillium sp. MMA, isolated from Sarcphyton glaucoma, afforded nine diverse compounds (1-9). Their structures were identified by 1D and 2 D NMR and ESI-MS spectroscopic data as two alkaloids: veridicatol (1), aurantiomide C (2); one sesquiterpene, aspterric acid (3); two carboxylic acids, 3,4-dihydroxy-benzoic acid; (4) and linoleic acid (5); three steroids, ergosterol (6), β-Sitosterol (7), β-Sitosterol glucoside (8) along with the sphingolipid, cerebroside A...
Source: Archives of Microbiology - Category: Microbiology Authors: Tags: Arch Microbiol Source Type: research
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Source: Japanese Journal of Ophthalmology - Category: Opthalmology Source Type: research
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