' Game Changer': Treat Diabetes and Also Reduce CV Risk'Game Changer': Treat Diabetes and Also Reduce CV Risk
Drs Shubrook and Chamberlain discuss cardiovascular risk reduction associated with SGLT-2 inhibitors and GLP-1 agonists in T2D, and advise clinicians to'be aware. 'Medscape Family Medicine
DIABETES type 2 symptoms include increased thirst, unexplained weight loss and frequently needing the toilet. Diabetes type 2 develops later in life due to risk factors including being overweight and having high blood pressure. New research has shown that eating in a 6-hour time period can prevent the condition.
Conclusion: The proposed simulator can be used to perform credible ISCT in realistic insulin treatment scenarios. Significance: The T1D patient decision simulator can be used to reliably assess novel insulin treatmen- s, e.g., based on use of CGM only, in a realistic multiple-day scenario.
People with diabetes mellitus need annual screening to check for the development of diabetic retinopathy (DR). Tracking small retinal changes due to early diabetic retinopathy lesions in longitudinal fundus image sets is challenging due to intra- and intervisit variability in illumination and image quality, the required high registration accuracy, and the subtle appearance of retinal lesions compared to other retinal features. This paper presents a robust and flexible approach for automated detection of longitudinal retinal changes due to small red lesions by exploiting normalized fundus images that significantly reduce il...
Is the short synacthen test a reliable means of assessing HPA axis recovery after long-term glucocorticoid treatment?Endocrine Practice
Conclusion: This case highlights the importance of recognizing gemcitabine-induced ischemic retinopathy that can be associated with life-threatening myocardial or renal ischemia.
Conclusion: Various studies have shown the safety and efficacy of intravitreal diclofenac without any reported side effect. We report the inner retinal toxicity in the form of cystic spaces and splitting of internal limiting membrane from nerve fiber layer on the first follow-up day, postinjection, which resolved over a period of 1 month. Further studies are needed to assess the safety of intravitreal diclofenac sodium.
Conclusion: In nephrotic syndrome cases especially with accompaniment of high blood pressure, fluid accumulation in the retina layer may occur. Serous macular detachment must be kept in mind when treating these patients.
CONCLUSION: The prevalence of NAFLD increases with increasing BMI and HBA1c in T2DM, while its ultrasound grade varies with BMI. Overweight, obesity and poor glycaemic control are independent predictors of NAFLD. PMID: 29778128 [PubMed - in process]
This study aims to determine the impact of early surgery and comorbid conditions on the outcomes of NSTIs.MethodsA retrospective cohort study was performed on all subjects presenting with NSTI at an academic medical center between 2005 and 2016. Patients were identified based on ICD codes. Those under the age of 18 or with intraoperative findings not consistent with NSTI diagnosis were excluded.ResultsThere were 115 patients with a confirmed diagnosis of NSTI with a mean age of 55 ± 18 years; 41% were females and 55% were diabetics. Thirty percent of patients underwent early surgery (
AbstractDiabetes mellitus (DM) epidemic —on a global scale—is a major and snowballing threat to public health, healthcare systems and economy, due to the cascade of pathologies triggered in a long-term manner after the DM manifestation. There are remarkable differences in the geographic disease spread and acceleration of an increasing DM prevalence recorded. Specifically, the highest initial prevalence of DM was recorded in the Eastern-Mediterranean region in 1980 followed by the highest acceleration of the epidemic characterised by 0.23% of an annual increase resulted in 2.3 times higher prevalence in the year...