Telangiectatic Matting is Associated with Hypersensitivity and a Bleeding Tendency.
CONCLUSION: TM is associated with both hypersensitivity and a bleeding tendency. This study revealed no significant increase in the incidence of haemostatic abnormalities in patients with TM compared with the control group. Given the significant association with hypersensitivity disorders, the underlying mast cell hyper-reactivity may contribute to both hypersensitivity and a bleeding tendency and predispose patients to TM. PMID: 29409702 [PubMed - as supplied by publisher]
ConclusionsLMWH does not increase the risk of post‐procedural bleeding and does not affect survival of cirrhotic patients undergoing prophylactic EVL.This article is protected by copyright. All rights reserved.
ConclusionsIntranasal bevacizumab injection is an effective treatment for most of the moderate and severe grades of HHT‐associated epistaxis. The duration of the effect of the treatment was variable. Primary and late resistance phenomena to the treatment were quite common. Level of Evidence4. Laryngoscope, 2018
Conclusions: SOCS3 was targeted by miR30a- 5p in AR. Further study should be performed to identify the regulatory effect of miR30a-5p in AR, which may provide insights into a new therapeutic strategy.Int Arch Allergy Immunol
Authors: Salzmann M, Hoesel B, Haase M, Mussbacher M, Schrottmaier WC, Kral-Pointner JB, Finsterbusch M, Mazharian A, Assinger A, Schmid JA Abstract Transfusion of platelet concentrates represents an important treatment for various bleeding complications. However, the short half-life and frequent contaminations with bacteria restrict the availability of platelet concentrates and raise a clear demand for platelets generated ex vivo. Therefore, in vitro platelet generation from megakaryocytes represents an important research topic. A vital step for this process represents accurate analysis of thrombopoiesis and propl...
This study aimed to compare skin measurements and investigate their correlations with various clinical severity scores. METHODS: Skin hydration (SH), transepidermal water loss (TEWL), pH, erythema, pigmentation and ITA (individual typology angle) were measured (using Delfin, Courage+Khazaka and Mettler Toledo equipment), and correlated with Patient-Oriented Eczema Measure (POEM, a short-term subjective-symptom score), Scoring Atopic Dermatitis (SCORAD, a short-term subjective-symptom and objective-sign score), Nottingham Eczema Severity Score (NESS, a long-term subjective-symptom score), Children Dermatology Life Quali...
CONCLUSIONS: EMR for NASDA is effective with a favorable long-term outcome. Local recurrences can be retreated endoscopically. A recall system, patient's compliance to endoscopic follow-up are mandatory to detect recurrences and their prompt treatment. PMID: 29458293 [PubMed - as supplied by publisher]
The most common disorders associated with an eosinophilia are infection (especially parasitic), allergy, drugs and hypersensitivity disorders (such as asthma, acute urticaria, and atopic dermatitis); these account for>95% of cases. Less common reactive causes are GVHD, Churg-Strauss syndrome, connective tissue and autoimmune disease. Literature talks less about it, although surgical mesh has been associated with more robust GVD and immune complications. There is a paucity of literature with respect to elderly with such conditions, even though the elders are more likely to have undergone such surgeries and therefore, at ...
Acquired Hemophilia A (AHA) is rare bleeding disorder caused by inhibitors (auto-antibodies) to factor VIIIA. (1,2) It is associated with severe bleeding. AHA clinical presentation is different from the inherited hemophilia that leads to misdiagnosis.
NEW YORK, Feb. 22, 2018 -- (Healthcare Sales &Marketing Network) -- Hoth Therapeutics Inc. ("Hoth" or the "Company"), a development stage biopharmaceutical company focused on unique targeted therapeutics for patients suffering from in... Biopharmaceuticals, Dermatology, Venture Capital Hoth Therapeutics, atopic dermatitis, eczema
CONCLUSIONS: This study is the first done in patients with allergic rhinitis and/or chronic urticaria using a F1-high speed simulator-driving test evaluating subjects' performance under bilastine treatment. PMID: 29461615 [PubMed - in process]