Effect of zoledronic-acid and alendronate on bone oedema and pain in spontaneous osteonecrosis of the knee: a new paradigm in medical management

Conclusion Our data shows that the combination therapy gives early pain relief and reduction of bone oedema, demonstrating to be and is safe, effective and well-tolerated for a painful disease entity like such as spontaneous osteonecrosis of knee.
Source: Revista Brasileira de Ortopedia - Category: Orthopaedics Source Type: research