Belong developing new social media app specifically for colorectal cancer patients

Living with cancer can be isolating, and finding the right resource to connect with others in the same situation can be tough. But one app is aiming to make the process easier for patients with its new social media platform.
Source: mobihealthnews - Category: Information Technology Source Type: news

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Condition:   Colorectal Cancer Intervention:   Sponsor:   State Scientific Centre of Coloproctology, Russian Federation Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
In this study, p53 wildtype (LoVo) and human p53 mutated (HT29 and SW480) colorectal cancer cells were treated with the miniFlatPlaSter - a device particularly developed for the treatment of tumor cells - that uses the Surface Micro Discharge (SMD) technology for plasma production in air. The present study analyzed the effects of plasma on colorectal cancer cells in vitro and on normal colon tissue ex vivo. Plasma treatment had strong effects on colon cancer cells, such as inhibition of cell proliferation, induction of cell death, and modulation of p21 expression. In contrast, CAP treatment of murine colon tissue ex vivo f...
Source: Biological Chemistry - Category: Chemistry Tags: Biol Chem Source Type: research
ACS NanoDOI: 10.1021/acsnano.8b03674
Source: ACS Nano - Category: Nanotechnology Authors: Source Type: research
The benefit of colonoscopy for colorectal cancer prevention depends on the adenoma detection rate (ADR). The ADR should reflect adenoma prevalence rate, estimated to be greater than 50% among the screening-age population. Yet the rate of adenoma detection by colonoscopists varies from 7% to 53%. It is estimated that every 1% increase in ADR reduces the risk of interval colorectal cancers by 3-6%. New strategies are needed to increase the ADR during colonoscopy. We tested the ability of computer-assisted image analysis, with convolutional neural networks (a deep learning model for image analysis), to improve polyp detection...
Source: Gastroenterology - Category: Gastroenterology Authors: Source Type: research
by Oriol Ros, Pablo Jos é Barrecheguren, Tiziana Cotrufo, Martina Schaettin, Cristina Roselló-Busquets, Alba Vílchez-Acosta, Marc Hernaiz-Llorens, Ramón Martínez-Marmol, Fausto Ulloa, Esther T. Stoeckli, Sofia J. Araújo, Eduardo Soriano Axonal growth and guidance rely on correct growth cone responses to guidance cues. Unlike the signaling cascades that link axonal growth to cytoskeletal dynamics, little is known about the crosstalk mechanisms between guidance and membrane dynamics and turnover. Recent studies indicate that wherea s axonal attraction requires exocytosis, chemorepul...
Source: PLoS Genetics - Category: Genetics & Stem Cells Authors: Source Type: research
Conclusion The interobserver and intermethod correlations for most of the histogram metrics of the DCE parameters are excellent in rectal cancer. Therefore, the single-section method may be a potential alternative to the whole-tumor volume method using pre-CRT MRI, despite the fact that the high agreement between the two methods cannot be extrapolated to post-CRT MRI.
Source: Diagnostic and Interventional Imaging - Category: Radiology Source Type: research
Publication date: 15 August 2018 Source:Journal of Organometallic Chemistry, Volume 869 Author(s): Mitat Akkoç, Sevgi Balcıoğlu, Canbolat Gürses, Tugba Taskin Tok, Burhan Ateş, Sedat Yaşar New benzimidazolium salts 1a-d having methylpyridine group on the side chain, have been synthesized and reacted with Ag2O to produce Ag(I)-N-heterocyclic carbene (NHC) complexes 2a-d. Ag(I)-N-heterocyclic carbene (NHC) complexes were used as a carben transfer agents to synthesize water-soluble ruthenium(II)-NHC complexes 4a-d. All synthesized compounds were fully characterized by 1H and 13C NMR and HRMS spectroscopic tec...
Source: Journal of Organometallic Chemistry - Category: Chemistry Source Type: research
Conclusion: We did not find variations in the OAR doses when each fraction was planned and treated individually. However, we found that if a single plan is used to treat subsequent fractions, OAR doses may exceed tolerance in about 30% of the cases. We believe that a larger sample size with improved compliance of bladder and bowel protocols would be needed to arrive at definitive conclusions.
Source: Journal of Medical Physics - Category: Physics Authors: Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
This study sought to develop a simple nanoparticle-based approach to enhance the efficiency and tolerability of lipopolysaccharide (LPS), a potent ligand of Toll-like Receptor 4 (TLR4), for immunotherapy in cancer. Despite holding promise within this context, the strong pro-inflammatory properties of LPS also account for its low tolerability given localized and systemic side effects, which restrict the administrable dosage. Herein, we investigated the effect of LPS decoration as a surface-active molecule on a polymeric matrix upon its efficiency and tolerability. The LPS-decorated nanoparticles (LPS-NP) were about 150&thin...
Source: Drug Delivery - Category: Drugs & Pharmacology Tags: Drug Deliv Source Type: research
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