Medical News Today: Stroke: Could looking into the eyes help with diagnosis?

A contrast agent given to stroke survivors undergoing MRI brain scans can leak into the eyes and may help to improve diagnosis and treatment.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Stroke Source Type: news

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A 11-year-old boy with genetically confirmed MELAS (mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome with mutation at mt.3243A>G) presented with extreme fatigue. He had elevated lactic acid of 5.2 mmol/L upon presentation. His magnetic resonance imaging (MRI) scan of the brain showed progression of multifocal gyral necrosis and cerebral atrophy compared to the images done 3 years prior to presentation (Fig. 1). He was discharged soon after his fatigue resolved in response to supportive therapy.
Source: Pediatric Neurology - Category: Neurology Authors: Source Type: research
AbstractBecause of concerns about the high risk of perioperative complications, the feasibility of minimally invasive aortic valve replacement (MIAVR) for elderly patients remains controversial. Here, we review our results of MIAVR in octogenarians with aortic valve stenosis (AS). Between October 2012 and December 2017, 110 patients with AS underwent MIAVR via a right anterolateral mini-thoracotomy; 41 patients were octogenarian (Group O). The perioperative outcomes of these patients were compared with those of the 69 patients who were less than 80  years of age (Group Y). A preoperative contrast-enhanced computed tom...
Source: Heart and Vessels - Category: Cardiology Source Type: research
We reported thatApoe deficiency resulted in a more extensive EBI at 48  h after SAH in mice demonstrated by MRI scanning and immunohistochemical staining and exhibited more extensive white matter injury and neuronal apoptosis than WT mice. These changes were associated with an increase in NADPH oxidase 2 (NOX2) expression, an important regulator of both oxidative stre ss and inflammatory cytokines. Furthermore, immunohistochemical analysis revealed that NOX2 was abundantly expressed in activated M1 microglia. The JAK2/STAT3 signaling pathway, an upstream regulator of NOX2, was increased in WT mice and activated to an ...
Source: Translational Stroke Research - Category: Neurology Source Type: research
Publication date: October 2018Source: Neuropsychologia, Volume 119Author(s): Matthew Ainsworth, Helen Browncross, Daniel J. Mitchell, Anna S. Mitchell, Richard E. Passingham, Mark J. Buckley, John Duncan, Andrew H. BellAbstractDamage following traumatic brain injury or stroke can often extend beyond the boundaries of the initial insult and can lead to maladaptive cortical reorganisation. On the other hand, beneficial cortical reorganisation leading to recovery of function can also occur. We used resting state FMRI to investigate how cortical networks in the macaque brain change across time in response to lesions to the pre...
Source: Neuropsychologia - Category: Neurology Source Type: research
There are three key characteristics evident on CT angiography (CTA) scans that...Read more on AuntMinnie.comRelated Reading: 5 risk factors help predict brain hemorrhage on CT AI algorithm can triage head CT exams for urgent review Perfusion imaging expands window for stroke treatment CTA helps direct use of clot removal for stroke patients Color mapping boosts vessel interpretation in stroke CT
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
AbstractIn clinical practice, direct oral anticoagulants (DOACs) are often started earlier ( ≤ 7 days) than in randomized clinical trials after stroke. We aimed to develop a nomogram model incorporating time of DOAC introduction ≤ 7 days of stroke onset in combination with different degrees of stroke radiological/neurological severity at the time of treatment to predict the prob ability of unfavorable outcome. We conducted a multicenter prospective study including 344 patients who started DOAC 1–7 days after atrial fibrillation-related stroke onset. Computed tomography scan 2...
Source: Journal of Thrombosis and Thrombolysis - Category: Hematology Source Type: research
If you delivered a baby early, you may want to pay closer attention to your heart health. A study published in the journal Hypertension shows that a history of preterm birth (defined as a birth before the 37th week of pregnancy) may bring health risks for not only for baby, but for mom, too. The study found that women who delivered a baby preterm were more likely to experience rising blood pressures later, compared to women who delivered closer to term. If they had this pattern, they were also more likely to show signs of coronary artery disease, which is associated with an increased risk of heart attack and stroke. Becaus...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Heart Health Pregnancy Women's Health Source Type: blogs
Authors: Befera N, Griffin AS, Hauck EF Abstract A 48-year-old woman presented with an acute ischemic stroke (National Institutes of Health Stroke Scale (NIHSS) 21) six hours after symptom onset. Workup revealed a left cervical internal carotid artery (ICA) occlusive dissection, which was emergently reconstructed with a flow-diverting stent. A routine Duplex scan one hour later suggested reocclusion of the ICA, confirmed by angiography. The true lumen of the ICA could not be accessed and therefore the "false lumen" of the ICA dissection was entered proximally. The true lumen and ultimately the flow-divert...
Source: Interventional Neuroradiology - Category: Radiology Tags: Interv Neuroradiol Source Type: research
AbstractMultiphase CT angiography (CTA) in collateral assessment provides time-resolved cerebral angiograms of the intracranial vasculature, requiring a high-speed multidetector CT (MDCT) scanner with ≥ 64 slices. Unfortunately, many hospitals are equipped with lower speed MDCT scanners. Herein, we present our experience performing dual-phase CTA (d-CTA) on a 16 slice MDCT with a biphasic rate injection to grade intracranial collaterals as predictor of clinical outcome. 42 patients were evalu ated with both dual-phase CTA (d-CTA) and single-phase CTA (s-CTA) for occluded anterior intracranial circulation and coll...
Source: Acta Neurologica Belgica - Category: Neurology Source Type: research
Conditions:   Stroke;   Dizziness;   Diplopia;   MRI;   Emergency Department Intervention:   Sponsor:   University Hospital, Strasbourg, France Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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