The daily lives of people with Parkinson's disease.

This study assists the improvement of care to people with the disease, because the care practice emerges from the interactions between the subjects. PMID: 29412283 [PubMed - in process]
Source: Revista Brasileira de Enfermagem - Category: Nursing Authors: Tags: Rev Bras Enferm Source Type: research

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Conclusion: Physical exercise contributes effectively to the treatment of PD, and can play a preventive and maintenance role of physical fitness and mental health. PMID: 29785199 [PubMed]
Source: Clinical Practice and Epidemiology in Mental Health - Category: Psychiatry Tags: Clin Pract Epidemiol Ment Health Source Type: research
Matej Skorvanek, Eva Feketeova, Monica M. Kurtis, Jan Rusz, Karel Sonka
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Yonglu Huang, Joshua P. Aronson, Julie G. Pilitsis, Lucy Gee, Jennifer Durphy, Eric Steven Molho, Adolfo Ramirez-Zamora
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Journal of Proteome ResearchDOI: 10.1021/acs.jproteome.8b00224
Source: Journal of Proteome Research - Category: Biochemistry Authors: Source Type: research
Publication date: August 2018 Source:Biomedicine & Pharmacotherapy, Volume 104 Author(s): Ali Khodadadian, Mohsen Hemmati-Dinarvand, Ashkan Kalantary-Charvadeh, Amin Ghobadi, Mahta Mazaheri Parkinson's disease (PD) is one of the most common diseases associated with neurodegenerative disorders. It affects 3% to 4% of the population over the age of 65 years. The neuropathological dominant symptoms of PD include the destruction of neurons in the substantia nigra, thus causing striatal dopamine deficiency and the presence of intracellular inclusions that contain aggregates of α‑synuclein. The premature form of PD ...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
α-Synuclein (α-Syn)-positive intracytoplasmic inclusions, known as Lewy bodies, are thought to be involved in the pathogenesis of Lewy body diseases, such as Parkinson's disease (PD). Although growing evidence suggests that cell-to-cell transmission of α-Syn is associated with the progression of PD and that extracellular α-Syn promotes formation of inclusion bodies, its precise mechanism of action in the extracellular space remains unclear. Here, as indicated by both conventional fractionation techniques and FRET-based protein–protein interaction analysis, we demonstrate that extracellular &al...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Signal Transduction Source Type: research
This study undertook a systematic meta-analysis of substantia nigra microarray data using the Transcriptome Mapper (TRAM) software to integrate and normalize a total of 10 suitable datasets from multiple sources. Four different analyses were performed according to default parameters, to better define the segments differentially expressed between PD patients and healthy controls, when comparing men and women data sets. The results suggest a possible regulation of specific sex-biased systems in PD susceptibility. TRAM software allowed us to highlight the different activation of some genomic regions and loci involved in molec...
Source: Genes - Category: Genetics & Stem Cells Authors: Tags: Article Source Type: research
Correction to: Ret is essential to mediate GDNF’s neuroprotective and neuroregenerative effect in a Parkinson disease mouse modelCorrection to: Ret is essential to mediate GDNF’s neuroprotective and neuroregenerative effect in a Parkinson disease mouse model, Published online: 25 May 2018; doi:10.1038/s41419-018-0636-4Correction to: Ret is essential to mediate GDNF’s neuroprotective and neuroregenerative effect in a Parkinson disease mouse model
Source: Cell death and disease - Category: Internal Medicine Authors: Source Type: research
Microglia-mediated neuroinflammation is recognized to mainly contribute to the pathogenesis of Parkinson ’s disease (PD). Tetrahydroxystilbene glucoside (TSG) has been proved to be beneficial for health with a ...
Source: Journal of Neuroinflammation - Category: Neurology Authors: Tags: Research Source Type: research
(MedPage Today) -- Pilot study shows promise for'on'Parkinson's patients
Source: MedPage Today Primary Care - Category: Primary Care Source Type: news
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