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The daily lives of people with Parkinson's disease.

This study assists the improvement of care to people with the disease, because the care practice emerges from the interactions between the subjects. PMID: 29412283 [PubMed - in process]
Source: Revista Brasileira de Enfermagem - Category: Nursing Authors: Tags: Rev Bras Enferm Source Type: research

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This article provides a comprehensive and historical review of MAOs and the state-of-the-art of these enzymes as membrane drug targets. PMID: 29464559 [PubMed - in process]
Source: Sub-Cellular Biochemistry - Category: Biochemistry Authors: Tags: Subcell Biochem Source Type: research
In conclusion and in agreement with the literature data, the prevalence of MCI recorded in the PACOS sample was approximately 40 and 32% amongst newly diagnosed patients.
Source: Journal of Neurology - Category: Neurology Source Type: research
Testing samples of an individual's tears for the presence of certain biomarkers could allow easier diagnosis of Parkinson's disease, a new study suggests.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
Abstract BACKGROUND: Astrocytes have been implicated as potentially exerting both neurotoxic and neuroprotective activities in Parkinson's disease (PD). Whether glial cells negatively impact the neuron integrity remains to be determined. We aimed to assess the vulnerability of glia and vessels in rat substantia nigra in a rotenone PD model. MATERIAL AND METHODS: Twenty adult male albino rats were divided into two equal groups: vehicle-control group (received dimethylsulfoxide + polyethylene glycol (PEG)-300, 1:1 v/v) and rotenone-treated group (received six doses of rotenone, 1.5 mg/kg/48 h s.c...
Source: Ultrastructural Pathology - Category: Pathology Authors: Tags: Ultrastruct Pathol Source Type: research
Condition:   Parkinson Disease Interventions:   Other: Shotokan-Karate;   Other: Tai-Chi Sponsor:   Sun Life Financial Movement Disorders Research and Rehabilitation Centre Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
A new study suggests that checking alpha-synuclein levels in tear samples may serve as a noninvasive test for Parkinson's disease before symptoms appear.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Parkinson's Disease Source Type: news
A new study suggests that checking alpha-synuclein levels in tear samples may serve as a noninvasive test for Parkinson's disease before symptoms appear.
Source: Parkinson's Disease News From Medical News Today - Category: Neurology Tags: Parkinson's Disease Source Type: news
When people shed tears, certain proteins are released. Levels of those proteins are different in people with Parkinson's compared to those without the disease, according to a preliminary study.
Source: WebMD Health - Category: Consumer Health News Source Type: news
This study presents a novel additive beneficial effect of NTF and STN DBS, which might be explained by the interaction of DBS-induced endogenous NTFs and exogenously injected CDNF. SNpc can be reached via similar trajectories used in clinical STN DBS, and this interaction is an important area for future studies.
Source: Neuroscience - Category: Neuroscience Source Type: research
Publication date: 10 May 2018 Source:Journal of Pharmaceutical and Biomedical Analysis, Volume 153 Author(s): Minhwa Oh, Eugene Huh, Myung Sook Oh, Ji-Seon Jeong, Seon-Pyo Hong We developed a diagnostic method for Parkinson's disease by simultaneously analyzing biogenic amines and their metabolites using reverse-phase high-performance liquid chromatography coupled with integrated pulsed amperometric detection (RP-HPLC-IPAD) method. Dopamine (DA), 3, 4-dihydroxyphenylacetic acid (DOPAC), serotonin (5-HT), 5-hydroxyindolacetic acid (5-HIAA), and homovanillic acid (HVA) were used as biomarkers to diagnose Parkinson's disease...
Source: Journal of Pharmaceutical and Biomedical Analysis - Category: Drugs & Pharmacology Source Type: research
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