A 27-Year-Old Woman With Facial Rash: USMLE Question A 27-Year-Old Woman With Facial Rash: USMLE Question
A 27-year-old woman presents with fatigue, joint pain, and facial rash. What study or investigation is the best next step?Osmosis
Anorectal pain and discomfort are common complaints in the general population, and can stem from a number of possible causes. Often, the complaints present in the primary care setting and can be adequately evaluated, diagnosed, and treated without the need for referral to a colorectal specialist. Proper evaluation and diagnosis can result in prompt, effective patient care. Recognition of red flags should prompt immediate referral to a colorectal specialist for further evaluation.
CONCLUSIONS: ISRs have been reported with ixekizumab during clinical trials. These reactions are typically tolerable, manageable, and decrease over time. Clinicaltrials.gov: NCT01474512 (UNCOVER-1); NCT01597245 (UNCOVER-2); NCT01646177 (UNCOVER-3); NCT01777191 (UNCOVER-A); NCT01624233 (UNCOVER-J); NCT01107457 (I1F-MC-RHAJ); NCT02561806 (I1F-MC-RHBS); NCT02387801 (I1F-US-RHBO);NCT02513550 (I1F-MC-RHBP); NCT02634801 (I1F-EW-RHBZ) J Drugs Dermatol. 2018;17(2):200-206. THIS ARTICLE HAD BEEN MADE AVAILABLE FREE OF CHARGE. PLEASE SCROLL DOWN TO ACCESS THE FULL TEXT OF THIS ARTICLE WITHOUT LOGGING IN. NO PURCHASE NECESSARY. PLEAS...
Peripheral nervous system damage from hematologic malignancies is related to neoplastic cells infiltration of peripheral nerves or to monoclonal antibody production cross-reacting with peripheral nerves' antigens. Neurolymphomatosis (NL), a rare manifestation of hematologic malignancies, occurs when malignant cells invade the peripheral nerves leading to various manifestations. Here, we report a case of NL with 2 hematologic malignancies in a 79-year-old woman presenting with lower extremity pain/weakness. Investigation revealed anemia, IgM kappa monoclonal gammopathy, and elevated anti-MAG titer. Electrodiagnostic studies...
We report a 27-year-old woman with a history of adenoid cystic carcinoma of the submandibular gland presented with painful twitching of her left shoulder. Electrodiagnostic studies were consistent with a diagnosis of radiation-induced spinal accessory nerve hyperactivity. The patient failed conventional medical therapy. She was treated with an injection of botulinum toxin A, and within 1 month experienced significant relief of symptoms. We thus conclude that Botulinum toxin is a therapeutic option for the pain associated with radiation-induced peripheral nerve hyperactivity.
ConclusionAn LFCN block consisting of 8 ml 0.75% ropivacaine had limited coverage of the posterior and lateral incision lines.
MORE than two in five of Britain's baby boomers are living in crippling pain but the majority suffer in silence and put off seeking treatment, a new report shows today.
ConclusionsMesalazine-induced myocarditis may be more common than first appreciated and is potentially fatal. Therefore, it is imperative that clinicians be aware of this potentially life-threatening adverse effect of mesalazine therapy and warn patients to seek urgent medical attention if cardiac symptoms arise.
Publication date: Available online 21 February 2018 Source:Journal of Orthopaedics Author(s): Giorgio Cacciola, Alessandro Pisani, Pietro Cavaliere, Bruno Pitrone, Domenico Rizzo, Giuseppina Rizzo, Giuseppina Cutroneo, Federico De Meo, Andrea Barbanera In humans the acquisition of the bipedalism caused different structural changes to achieve the new functional demands. In particular, several changes have occurred to the spine and pelvis. In recent years the sagittal morphology of the spine and pelvis has become one of the most focused topics in spine research. The sample consists of 348 volunteers, with no history of low ...
Conclusion The use of a rotating-hinge implant for knee arthroplasty is a new option for complex cases with severe instability in Brazil; the initial results are satisfactory.