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Publication date: Available online 23 October 2018Source: The Veterinary JournalAuthor(s): R. Ricci, A. Perazzi, T. Badon, S. Bedin, I. IacopettiAbstractResearch or diagnostic conditions may require the storage of salivary samples for long periods before analysis is processed. The aim of this study was to evaluate the stability of canine salivary α-amylase, lysozyme, lactate dehydrogenase (LDH), and total calcium and phosphorus after storage for 1, 3 and 6 months at −20 °C. Available saliva samples were 75 immediately after collection (T0) and 46 at 1 month (T1), 31 at 3 months (T3) and 18 at 6 months ...
ConclusionsIn large animal veterinary medicine, SR-MA are uncommonly performed in equine and bovine medicine. The SR-MA can be assessed using AMSTAR with acceptable inter-rater reliability, which is helpful to assess SR-MA methodological quality.
Publication date: Available online 22 October 2018Source: Research in Veterinary ScienceAuthor(s): Enrica Sozzi, Ana Moreno, Davide Lelli, Simona Perulli, Alice Prosperi, Emiliana Brocchi, Lorenzo Capucci, Alice Papetti, Enrico Giacomini, Giovanni Loris Alborali, Antonio LavazzaAbstractPorcine epidemic diarrhoea virus (PEDV), belongs to the genus Alphacoronavirus in the family Coronaviridae and causes severe diarrhoea, vomiting, dehydration and high mortality in seronegative newborn piglets. Thus, a precise and rapid diagnosis of PEDV infection is important for the application of control measures to limit viral disseminati...
Publication date: Available online 22 October 2018Source: Research in Veterinary ScienceAuthor(s): Pallavi Bhardwaj, Pritam K. Sidhu, M.K. Lonare, Rajdeep Kaur, V.K. Dumka, S. RampalAbstractThe single dose pharmacokinetics (PK) of marbofloxacin was compared with repeated intravenous (IV) administrations in six healthy goats at the dose rate of 2 mg/kg body weight at 24 h interval for 5 days. Blood samples were collected at times: 5, 15, 30 min and 1, 2, 4, 6, 9, 12, 24, 36, 48 and 72 h post drug administration. Plasma drug concentrations were determined by High Performance Liquid Chromatography and concentration-...
Authors: PMID: 30347455 [PubMed - in process]
This article reviews the state-of-the-art in transporter clinical probe drugs and emerging biomarkers, including current challenges and limitations, delineates methods and workflows to identify and validate novel endogenous biomarkers to support clinical DDI evaluations, and proposes how these probe drugs or biomarkers could be used in drug development. PMID: 30347454 [PubMed - in process]
Authors: PMID: 30347453 [PubMed - in process]
Authors: PMID: 30347452 [PubMed - in process]
Authors: PMID: 30347451 [PubMed - in process]
Authors: PMID: 30347450 [PubMed - in process]
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