Primary Prevention ICD Efficacy Again Questioned in HF With CKD Primary Prevention ICD Efficacy Again Questioned in HF With CKD

Clinical trials left big questions about implantable defibrillator efficacy in patients with chronic kidney disease; a new cohort study casts doubt on whether they prolong survival in such cases.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Cardiology News Source Type: news

Related Links:

Authors: Șerban RC, Șuș I, Lakatos EK, Demjen Z, Ceamburu A, Fișcă PC, Somkereki C, Hadadi L, Scridon A Abstract BACKGROUND: Atrial fibrillation (AF) often complicates ST-segment elevation myocardial infarction (STEMI). Predictors of AF in this setting include factors related to the acute phase of STEMI and pre-existing conditions. More recently, novel AF predictors have been identified in the general population. We aimed to assess the ability of such novel factors to predict STEMI-related AF. METHODS: Data were collected from STEMI patients treated by primary PCI. Factors related to the acute phase of STE...
Source: Acta Cardiologica - Category: Cardiology Tags: Acta Cardiol Source Type: research
Authors: Klug E, Raal FJ, Marais AD, Smuts CM, Schamroth C, Jankelow D, Blom DJ, Webb DA Abstract South Africa (SA) is home to a heterogeneous population with a wide range of cardiovascular risk factors. Cholesterol reduction in combination with aggressive management of modifiable risk factors, including nutrition, physical activity, blood pressure and smoking, can help to reduce and prevent morbidity and mortality in individuals who are at increased risk of cardiovascular events. This updated consensus guide to management of dyslipidaemia in SA is based on the updated European Society of Cardiology and European At...
Source: South African Medical Journal - Category: African Health Tags: S Afr Med J Source Type: research
A 52-year-old man with diabetes mellitus, congestive heart failure, morbid obesity (body mass index: 37), and chronic kidney disease started peritoneal dialysis using a surgically inserted catheter (midline incision). Catheter dysfunction necessitated surgical repositioning. During the operation, a cavity localized in the subcutaneous fat of the abdominal wall was discovered, with connection to the peritoneum space and the entire catheter within the cavity. The malfunctioning catheter was replaced through the same insertion site without an attempt to fix the cavity.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Nephrology Image Source Type: research
To compare outcomes in patients with normal, moderate and severe chronic kidney disease undergoing endovascular abdominal aortic aneurysm repair (EVAR) using devices with and without suprarenal fixation.
Source: Annals of Vascular Surgery - Category: Surgery Authors: Tags: Abstracts Presented to the Vascular and Endovascular Surgery Society - 2019 Annual Winter Meeting Source Type: research
Authors of the CRIC study found sex-related disparities in chronic kidney disease progression. Scroll through our slideshow to get the highlights.  
Source: ConsultantLive - Category: Internal Medicine Authors: Tags: Kidney Disease Source Type: news
Discussion: Elevated malnutrition risk is a frequent finding in HD patients treated in hospital settings in Israel. Dietary intake does not meet guidelines but does not differ across malnutrition risk categories. Nutrition supplements are underused in HD patients with high malnutrition risk. There is a need to expand the survey to community HD centers.Nephron
Source: Nephron - Category: Urology & Nephrology Source Type: research
Abstract Clock gene dysregulation has been shown to underlie various sleep disorders and may lead to negative cardio-metabolic outcomes. However, the association between sleep apnea(SA) and core clock gene expression is unclear. We performed a cross-sectional analysis of 49 Veterans enrolled in a study of SA outcomes in Veterans with chronic kidney disease, not selected for SA or sleep complaints. All participants underwent full polysomnography and next morning whole blood collection for clock gene expression. We defined SA as an apnea-hypopnea index (AHI)≥15 events/hour; nocturnal hypoxemia(NH) was defined as ...
Source: Physiological Reviews - Category: Physiology Authors: Tags: Physiol Genomics Source Type: research
AbstractPurposeTo evaluate the association between obesity phenotypes and health-related quality of life (HRQoL) in non-dialysis-dependent CKD patients.MethodsData from the national CKD-REIN cohort which included 3033 patients with stage 3 –4 CKD were used. Patients were divided into three groups: non-obese (NO) patients (BMI 
Source: Quality of Life Research - Category: Health Management Source Type: research
In this study we evaluated the potential for knockdown or overexpression of miR-21-5p to regulate lipid content, peroxidation and mitochondrial respiration in H9C2 cells. Cells were transfected with anti-miR-21-5p (40nM), pre-miR-21-5p (20nM) or scrambled oligonucleotide controls prior to lipid treatment in culture, or as part of the Agilent Seahorse XF fatty acid oxidation assay. Overexpression of miR-21-5p attenuated the lipid induced increase in cellular lipid content, while suppression of miR-21-5p augmented it. The abundance of malondialdehyde (MDA), a product of lipid peroxidation, was significantly increased with li...
Source: American Journal of Physiology. Heart and Circulatory Physiology - Category: Physiology Authors: Tags: Am J Physiol Heart Circ Physiol Source Type: research
Chronic kidney disease (CKD), which affects people of all ages, can result in chronic renal failure, its most significant outcome.
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Resource Center Source Type: news
More News: Cardiology | Chronic Kidney Disease | Clinical Trials | Health | Heart | Study | Urology & Nephrology