MS Drug Poses Hard Choices for Women Wanting Kids

Those who take Tysabri (natalizumab) to manage their MS are more likely to suffer a relapse during pregnancy if they stop taking the drug before they conceive, the first study found.
Source: WebMD Health - Category: Consumer Health News Source Type: news

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This study aimed to clarify functions of uterine HIF using transgenic mouse models. Mice with deletion of Hif2a in the whole uterus (Hif2a-uKO mice) showed infertility due to implantation failure. Supplementation with progesterone (P4) and leukemia inhibitory factor (LIF) restored decidual growth arrest and aberrant position of implantation sites in Hif2a-uKO mice, respectively, but did not rescue pregnancy failure. Histological analyses in Hif2a-uKO mice revealed persistence of the intact luminal epithelium, which blocked direct contact between stroma and embryo, inactivation of PI3K-AKT pathway (embryonic survival signal...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Abstract: Subcutaneous fat necrosis of the newborn is a rare benign panniculitis found in term and post-term neonates. Diagnosis is based on clinical characteristics and specific alterations in the adipocytes, detected by anatomical pathology. Subcutaneous fat necrosis of the newborn can occur in uncomplicated pregnancy and childbirth. However, perinatal complications such as asphyxia, hypothermia, seizures, preeclampsia, meconium aspiration, and even whole-body cooling used in newborns with perinatal hypoxia/anoxia may be associated with this entity.
Source: Anais Brasileiros de Dermatologia - Category: Dermatology Source Type: research
Conclusion: In this study, PABC showed lower expression of ER/PR, higher overexpression of HER2, fewer luminal A subtype, and more TNBC subtype compared to YBC. PABC had worse BCSS, especially luminal B subtype, compared to YBC.Oncology
Source: Oncology - Category: Cancer & Oncology Source Type: research
Valeria Garcia-Flores, Roberto Romero, Derek Miller, Yi Xu, Bogdan Done, Chharitha Veerapaneni, Yaozhu Leng, Marcia Arenas-Hernandez, Nabila Khan, Bogdan Panaitescu, Sonia S. Hassan, Luis Marat Alvarez-Salas, Nardhy Gomez-Lopez
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
By Michelle Catenacci, M.DCHICAGO, Jun 18 2018 (IPS)Fertility health is an incredibly personal – and often vulnerable – topic. Fertility, infertility, and fertility preservation have gained increased public interest over the past few years. Infertility is formally defined as the inability to achieve pregnancy after one year of unprotected intercourse. The Centers for Disease Control and Prevention (CDC) reports that approximately 12% of women aged 15 to 44 in the United States have difficulty getting pregnant or carrying a pregnancy to term. Even though a significant proportion of the population suffers from th...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Aid Education Featured Gender Global Headlines Health Population Poverty & SDGs TerraViva United Nations Source Type: news
[Vanguard] A MOTHER, Mrs. Esther Akinola and her baby are currently stranded at the Lagos University Teaching Hospital, LUTH, over inability to settle a N306,200 bill.
Source: AllAfrica News: Pregnancy and Childbirth - Category: OBGYN Source Type: news
OBJECTIVE: To estimate the prevalence of intimate partner violence( IPV)during pregnancy in two cities of Anhui, China. Also, to investigate the association of spontaneous preterm birth with IPV during pregnancy. METHODS: In a cross-sectional study...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
ConclusionsHigh rates of recurrent normal/abnormal karyotypes were observed in all groups with a majority of embryos presenting with recurrent abnormal morphology. Secondary RPL presented significantly more often with recurrent abnormal morphology compared to primary RPL. These findings offer prognostic information for the affected patient and might impact treatment choice.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
This study aims to estimate the preval...
Source: BMC Public Health - Category: Consumer Health News Authors: Tags: Research article Source Type: research
AbstractTattoos are becoming increasingly common and are the result of a variety of underlying motivations. Patients with medical or skin conditions should be advised of the tattooing-related risks and recommendations specific for their condition. Tattooing is strictly contraindicated in only a few medical/skin conditions (i.e. pregnancy, breastfeeding, severe immunosuppression, tumour-related scars). In other medical/skin conditions, tattoo-related risks should be considered and recommendations and precautions followed.
Source: Drugs and Therapy Perspectives - Category: Drugs & Pharmacology Source Type: research
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