[ 11 C]Harmine Binding to Brain Monoamine Oxidase A: Test-Retest Properties and Noninvasive Quantification

ConclusionsProspective studies using [11C]harmine are possible given its test-retest repeatability when binding is quantified using arterial blood. Results with SIME of input function show potential for simplifying data acquisition by replacing arterial catheterization with one arterial blood sample at 20  min post-injection. Estimation of [11C]harmine binding potentials remains a challenge that warrants further investigation.
Source: Molecular Imaging and Biology - Category: Molecular Biology Source Type: research