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Zimbabwe:First Lady Screened for Cervical, Breast Cancer

[The Herald] Firsty Lady Auxillia Mnangagwa was yesterday screened for cervical and breast cancer at United Bulawayo Hospitals (UBH) as a way of motivating women to do the same as the country intensifies the fight against the silent killer.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news

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[Independent (Kampala)] Kampala -As early as 9am on Feb.09, people had started gathering at Centenary Park. It was yet another 'free medical camp'. Organized by the Mulago hospital based College of Health Sciences, people would at this camp get free checkups for cervical cancer, breast cancer, hypertension and dental care among others. Organisers of the camp were just starting to hang the banners and set up tables but people were already queuing. I sensed it could get crowded.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Publication date: Available online 17 February 2018 Source:Journal of Cancer Policy Author(s): Tingting Xu, Jing Wu Cancer is not only a medical problem, but also a socio-economical issue as the high prevalence with poor prognosis brings heavy financial burden to the society. From 2005 to 2013, the incidence and mortality rates have sharply increased in China. The most common types of cancer in males in China are lung cancer, gastric cancer, liver cancer, colorectal cancer and esophageal cancer while breast cancer, lung cancer, colorectal cancer, gastric cancer, and cervical cancer are the major types of cancer among Chin...
Source: Journal of Cancer Policy - Category: Cancer & Oncology Source Type: research
Abstract Regioisomers of the functional group of the main ligand (L) on a series of [Ru(phen)2L]2+and [Ru(bpy)2L]2+ complexes, where phen is 1,10 phenanthroline and bpy is 2,2'-bipyridine, were synthesised to investigate the interaction with deoxyribonucleic acid (DNA) as potential therapeutics. UV-Vis binding titrations, thermal denaturation and circular dichroism were used to evaluate their interaction with DNA. The conclusions indicated the significance of the auxiliary ligand; especially 1,10-phenanthroline has on the binding constants (Kb). The systematic variation of auxiliary ligand(phen or bpy), and polypy...
Source: Journal of Inorganic Biochemistry - Category: Biochemistry Authors: Tags: J Inorg Biochem Source Type: research
Excerpted fromPrecision Medicine and the Reinvention of Human DiseaseDespite having the most advanced healthcare technology on the planet, life expectancy in the United States is not particularly high. Citizens from most of the European countries and the highly industrialized Asian countries enjoy longer life expectancies than the United States. According to the World Health Organization, the United States ranks 31st among nations, trailing behind Greece, Chile, and Costa Rica, and barely edging out Cuba [42]. Similar rankings are reported by the US Central Intelligence Agency [43]. These findings lead us to infer that acc...
Source: Specified Life - Category: Information Technology Tags: cancer cancer vaccines precision medicine prevention public health Source Type: blogs
[Daily News] WHILE national records cite cervical cancer as the second most troublesome disease in Tanzania behind breast cancer, the Aga Khan hospital has slotted colorectal cancer in the position.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Conclusion Alpelisib demonstrated a tolerable safety profile and encouraging preliminary activity in patients with PIK3CA-altered solid tumors, supporting the rationale for selective PI3Kα inhibition in combination with other agents for the treatment of PIK3CA-mutant tumors. PMID: 29401002 [PubMed - as supplied by publisher]
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Tags: J Clin Oncol Source Type: research
AbstractIn order to find new anticancer drugs, a series of novel furoxan-based coumarin derivatives (10a–k) were synthesized and evaluated for their antiproliferative activities in vitro. All compounds displayed more potent inhibition on human cervical cancer HeLa cell proliferation than coumarin-3-carboxylic acid, and compounds10b, 10c, 10f, 10h, and10i with IC50 values ranging from 0.88 to 5.95  μM were even stronger than doxorubicin (IC50 = 10.21 μM). The further study showed that compound10i exerted the highest antiproliferative activity (IC50 = 0.60 μM) a...
Source: Medicinal Chemistry Research - Category: Chemistry Source Type: research
Conclusion In general, these incidence patterns were similar to those reported in neighboring countries, which suggests that the majority of cancer cases occurring in Addis Ababa are captured within this starting phase of the registry. However, our finding of colorectal cancer as the most commonly-diagnosed cancer in males is novel and requires further investigation.
Source: Cancer Epidemiology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 1 February 2018 Source:Acta Pharmaceutica Sinica B Author(s): Jian Chen, Xiaona Fan, Jianhua Zhu, Liyan Song, Zhiwei Li, Fei Lin, Rongmin Yu, Hanhong Xu, Jiachen Zi Four new limonoid-type nortriterpenoids, 1-detigloyl-1-O-methacryloylsalannin (1), 28-deoxo-2,3-dihydronimbolide (2), 12-acetoxy-3-O-acetyl-7-O-tigloylvilasinin (3) and 12-acetoxy-3-O-acetyl-7-O-methacryloylvilasinin (4), along with five known ones, were isolated from seeds of Azadirachta indica A. Juss. Their structures were elucidated by various spectroscopic methods, including UV, IR, MS, NMR, X-ray crystallography, quantu...
Source: Acta Pharmaceutica Sinica B - Category: Cancer & Oncology Source Type: research
The TFCP2/Grainyhead family of transcription factors is divided into two distinct subfamilies, one of which includes the Grainyhead-like 1-3 (GRHL1-3) proteins and the other consists of TFCP2 (synonyms: CP2, LSF, LBP-1c), TFCP2L1 (synonyms: CRTR-1, LBP-9) and UBP1 (synonyms: LBP-1a, NF2d9). Transcription factors from the TFCP2/TFCP2L1/UBP1 subfamily are involved in various aspects of cancer development. TFCP2 is a pro-oncogenic factor in hepatocellular carcinoma, pancreatic cancer and breast cancer, may be important in cervical carcinogenesis and in colorectal cancer.
Source: Cancer Letters - Category: Cancer & Oncology Authors: Tags: Mini-review Source Type: research
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