Assessment of tobacco heating product THP1.0. Part 4: Characterisation of indoor air quality and odour

Publication date: March 2018 Source:Regulatory Toxicology and Pharmacology, Volume 93 Author(s): Mark Forster, John McAughey, Krishna Prasad, Eleni Mavropoulou, Christopher Proctor The tobacco heating product THP1.0, which heats but does not burn tobacco, was tested as part of a modified-risk tobacco product assessment framework for its impacts on indoor air quality and residual tobacco smoke odour. THP1.0 heats the tobacco to less than 240 °C ± 5 °C during puffs. An environmentally controlled room was used to simulate ventilation conditions corresponding to residential, office and hospitality environments. An analysis of known tobacco smoke constituents, included CO, CO2, NO, NO2, nicotine, glycerol, 3-ethenyl pyridine, sixteen polycyclic aromatic hydrocarbons, eight volatile organic compounds, four carbonyls, four tobacco-specific nitrosamines and total aerosol particulate matter. Significant emissions reductions in comparison to conventional cigarettes were measured for THP1.0. Levels of nicotine, acetaldehyde, formaldehyde and particulate matter emitted from THP1.0 exceeded ambient air measurements, but were more than 90% reduced relative to cigarette smoke emissions within the laboratory conditions defined Residual tobacco smoke odour was assessed by trained sensory panels after exposure of cloth, hair and skin to both mainstream and environmental emissions from the test products. Residual tobacco smoke odour was significantly lower from THP1.0 ...
Source: Regulatory Toxicology and Pharmacology - Category: Toxicology Source Type: research

Related Links:

Rebecca McKetin, Alexandra Voce, Richard Burns, Robert Ali, Dan I. Lubman, Amanda L. Baker, David J. Castle
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Publication date: Available online 17 November 2018Source: Polymer TestingAuthor(s): Julia Radwan-Pragłowska, Marek Piątkowski, Łukasz Janus, Dariusz Bogdał, Dalibor Matysek, Vladimir CablikAbstractTissue engineering provides solutions for patients awaiting for transplantation. Tissue engineering solutions help doctors to deliver tissue equivalent to damaged tissue. Such treatment method requires advanced biomaterials which would not only enable cells proliferation but also help to maintain their viability. The aim of the present work was to develop new chitosan-based biomaterial with enhanced properties applicable in ...
Source: Polymer Testing - Category: Chemistry Source Type: research
Publication date: Available online 17 November 2018Source: MethodsXAuthor(s): Christie M. Hawley, E. Louise Loudermilk, Eric M. RowellABSTRACTSurface fuels are the critical link between structure and function in frequently burned pine ecosystems, which are found globally [1,2,3]. We bring fuels to the forefront of fire ecology through the concept of the Ecology of Fuels [4]. This concept describes a cyclic process between fuels, fire behavior, and fire effects, which ultimately affect future fuel distribution [5]. Low-intensity surface fires are driven by the variability in fine-scale (sub-m level) fuels [6]. Traditional f...
Source: MethodsX - Category: Science Source Type: research
Publication date: Available online 17 November 2018Source: The Annals of Thoracic SurgeryAuthor(s): Kimberly E. McHugh, William T. Mahle, Matthew A. Hall, Mark A. Scheurer, Michael-Alice Moga, John Triedman, Susan C. Nicolson, Venugopal Amula, David S. Cooper, Marcus Schamberger, Michael Wolf, Lara Shekerdemian, Kristin M. Burns, Kathleen E. Ash, Dustin M. Hipp, Sara K. Pasquali, Pediatric Heart Network InvestigatorsAbstractBackgroundThe Pediatric Heart Network Collaborative Learning Study (PHN CLS) increased early extubation rates after infant Tetralogy of Fallot (TOF) and coarctation (CoA) repair across participating sit...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
We report the in situ synthesis of hydroxyapatite nanoparticles on 1-3 layers of colloidal collagen-graphene composites. Varying calcium and phosphate : graphene ratio two different composites were synthesized. Crystallite size, particle size and degree of crystallinity of hydroxyapatite nanoparticles changes with a change in graphene concentration. Transmission electron microscopy shows that these graphene composites change shape from spherical to elongated needle-like structures because of the varying nitrogen content in collagen-graphene. Fourier-transform Infrared Spectroscopy peaks suggests an interaction between calc...
Source: Materials Today Communications - Category: Materials Science Source Type: research
Veterans with blast-related mild traumatic brain injury (mTBI) report difficulty engaging in life roles, also referred to as participation. Current measures are either global or lack comprehensive coverage of life roles and have not been validated in Veter...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news
That fire facilitated the late Miocene C4 grassland expansion is widely suspected but poorly documented. Fire potentially tied global climate to this profound biosphere transition by serving as a regional-to-local driver of vegetation change. In...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news
INTRODUCTION: Psychiatric disorders are mental illnesses that impair judgment, thought process and mood that can result in physical and emotional disability. According to DSM-IV, mental disorders increases risk of traumatic injury, particularly burn [1] (A...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news
The use of fire by cattle ranchers is a major source of conflict between conservationists and local communities in tropical savannas. We evaluate the role of traditional pastoral management in wildfire prevention in two protected areas within the Brazilian...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news
Objectives: To identify, appraise, and synthesize current evidence to determine whether early enteral nutrition alters patient outcomes from major burn injury. Data Sources: Medline, Embase, and the China National Knowledge Infrastructure were searched. The close out date was May 1, 2018. Study Selection: Early enteral nutrition was defined as a standard formula commenced within 24 hours of injury or admission to ICU or burn unit. Comparators included any form of nutrition support “except” early enteral nutrition. Only randomized controlled trials reporting patient-centered outcomes were eligible for in...
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Review Articles Source Type: research
More News: Burns | Drugs & Pharmacology | Environmental Health | Laboratory Medicine | Nicotine | Organic | Skin | Smokers | Toxicology