Medical News Today: Could looking into the eyes aid stroke diagnosis?

A contrast agent given to stroke survivors undergoing MRI brain scans can leak into the eyes and may help to improve diagnosis and treatment.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Stroke Source Type: news

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Publication date: Available online 10 November 2018Source: Biochimica et Biophysica Acta (BBA) - BiomembranesAuthor(s): Erika Reus-Chavarría, Ivette Martínez-Vieyra, Cristina Salinas-Nolasco, Araceli Evangelina Chávez-Piña, Juan Vicente Méndez-Méndez, Edgar Oliver López-Villegas, Alejandro Sosa-Peinado, Doris CerecedoAbstractHypertension (HTN), i.e. abnormally high blood pressure, is a major risk factor for heart attack, stroke, and kidney failure. The Epithelial Sodium Channel (ENaC), one of the main transporters regulates blood pressure by tightly controlling the sodium re...
Source: Biochimica et Biophysica Acta (BBA) Biomembranes - Category: Biochemistry Source Type: research
We present a case report of a 69-year-old man who on unenhanced PMCT scan showed an empty delta sign in the cerebral veins. The empty delta sign was able to be demonstrated in unenhanced PMCT which can be explained by hyper attenuation of the dural veins at postmortem forming an internal contrast highlighting the thrombus.
Source: The American Journal of Forensic Medicine and Pathology - Category: Forensic Medicine Tags: Case Reports Source Type: research
ConclusionThe ECASS classification may involve too many categories and the diagnosis of HT may not be easily replicable, except in the presence of a large parenchymal hematoma.This article is protected by copyright. All rights reserved.
Source: European Journal of Neurology - Category: Neurology Authors: Tags: Original Article Source Type: research
Publication date: Available online 8 November 2018Source: The Lancet NeurologyAuthor(s): David J Seiffge, David J Werring, Maurizio Paciaroni, Jesse Dawson, Steven Warach, Truman J Milling, Stefan T Engelter, Urs Fischer, Bo NorrvingSummaryBackgroundAbout 13–26% of all acute ischaemic strokes are related to non-valvular atrial fibrillation, the most common cardiac arrhythmia globally. Deciding when to initiate oral anticoagulation in patients with non-valvular atrial fibrillation is a longstanding, common, and unresolved clinical challenge. Although the risk of early recurrent ischaemic stroke is high in this populat...
Source: The Lancet Neurology - Category: Neurology Source Type: research
Diffusion Tensor-Derived Properties of Benign Oligemia, True "at Risk" Penumbra, and Infarct Core during the First Three Hours of Stroke Onset: A Rat Model. Korean J Radiol. 2018 Nov-Dec;19(6):1161-1171 Authors: Chiu FY, Kuo DP, Chen YC, Kao YC, Chung HW, Chen CY Abstract Objective: The aim of this study was to investigate diffusion tensor (DT) imaging-derived properties of benign oligemia, true "at risk" penumbra (TP), and the infarct core (IC) during the first 3 hours of stroke onset. Materials and Methods: The study was approved by the local animal care and use committee. DT ...
Source: Korean Journal of Radiology - Category: Radiology Tags: Korean J Radiol Source Type: research
ConclusionsAge and marked WMH at index stroke, but not stroke subtype, predicted long ‐term WMH progression after ischemic stroke before 70 years of age, whereas age and hypertension predicted acquisition of marked WMH in those with no or only mild WMH at baseline.
Source: Acta Neurologica Scandinavica - Category: Neurology Authors: Tags: ORIGINAL ARTICLE Source Type: research
ConclusionsHyperthermia within 3  days after rt‐PA is associated with poor functional prognosis and survival outcome in patients with acute cerebral infarction.
Source: Acta Neurologica Scandinavica - Category: Neurology Authors: Tags: CLINICAL COMMENTARY Source Type: research
Conclusions: There are limited reports of protamine reversal of heparin before IV-tPA administration. To our knowledge, there are only 6 AIS cases including ours. Three cases received 0.6 mg/kg of tPA dose. All have favorable outcomes and no intracranial hemorrhage was reported. Protamine reversal of heparin for AIS after CC seems to be safe. Further studies are needed to confirm the therapeutic safety and efficacy of this strategy.
Source: The Neurologist - Category: Neurology Tags: Case Report/Case Series Source Type: research
The objective of this study is to evaluate [11C]TMI, a selective COX-2 inhibitor (Ki ≤ 1 nM) in nonhuman primates using PET imaging. PET imaging in baboons showed that [11C]TMI penetrates the blood brain barrier (BBB) and accumulates in brain in a somewhat heterogeneous pattern. Metabolite analyses indicated that [11C]TMI undergoes no significant metabolism of parent tracer in the plasma for baseline scans, however a relative faster metabolism was found for blocking scan. All the tested quantification approaches provide comparable tracer total distribution volume (VT) estimates in the range of 3.2-7 (mL/cm3). We...
Source: Bioorganic and Medicinal Chemistry Letters - Category: Chemistry Authors: Tags: Bioorg Med Chem Lett Source Type: research
Talking, conversing, exchanging words: for more than 10 million people, this seemingly simple act cannot be imagined without assistive technologies, such as voice generating devices, touch screens or text-to-speech apps. What does the digital future bring for them? How could innovations turn around the translation industry or the medical administration process? Here’s a glimpse into the future of voice and speaking. Speaking, identity, voice stereotypes Give me the key! – This simple sentence carries much more information when it’s pronounced. A weary Philippino mother could instruct her little child as s...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Cyborgization Future of Medicine Medical Professionals Patients apps assistive technology Health Healthcare Innovation speaking speech speech generating voice voice generating device Source Type: blogs
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