Regeneron CEO says fears over Eylea 'greatly exaggerated'

(Reuters) - Fears of the demise of blockbuster eye drug Eylea were "greatly exaggerated," Regeneron Pharmaceuticals Inc's chief executive said on Thursday, after the treatment and new eczema drug Dupixent powered the company's fourth-quarter results.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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AbstractPurpose of ReviewThe hyper IgE syndromes (HIES) comprise a group of rare primary immunodeficiency disorders (PIDDs), which are characterized by extremely high serum IgE levels, eczema, recurrent skin and pulmonary infections. Both autosomal dominant (AD) HIES due to STAT3 mutations and autosomal recessive (AR) HIES due to PGM3, SPINK5, DOCK8 and TKY2 mutations have been reported. Here, we aim to summarize and compare the major clinical manifestations of different subtypes of HIES. We will also discuss otitis media, which usually do not get enough attention in HIES. Update and familiarity with these clinical feature...
Source: Current Allergy and Asthma Reports - Category: Allergy & Immunology Source Type: research
Conditions:   Keloid;   Alopecia Areata;   Acne;   Hypertrophic Scar;   Epidermal Inclusion Cyst;   Frontal Fibrosing Alopecia;   Lichen Plano-Pilaris;   Keratoacanthoma;   Plaque Psoriasis;   Lichen Simplex Chronicus;   Prurigo Nodularis;   Nummular Eczema;   Granuloma Annulare;   M orphea;   Lichen Planus Interventions:   Drug: Corticosteroid with lidocaine;   Drug: Corticosteroid with normal saline Sponsor:   Vanderbilt Uni...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ECZEMA could be treated with creams, ointments or moisturisers. But how can you get rid of the dry skin condition at home? These are the best ways to prevent an eczema rash on your hands, face or knees.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Conditions:   Dermatitis;   Dermatitis, Atopic;   Eczema;   Skin Diseases;   Skin Diseases, Genetic;   Genetic Diseases, Inborn;   Skin Diseases, Eczematous;   Hypersensitivity;   Hypersensitivity, Immediate;   Immune System Diseases Interventions:   Drug: PF-04965842 100 mg;   Drug: PF-04965842 200 mg;   Drug: Placebo Sponsor:   Pfizer Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
It’s no exaggeration to say that lives are transformed by the Wheat Belly lifestyle. Look what happened to Susanne after her health was ruined by being gluten-free, reversed by following the Wheat Belly 10-Day Grain Detox. Food manufacturers, out of ignorance or ruthless profiteering, have chosen to replace wheat and gluten with cornstarch, rice flour, tapioca starch, or potato starch—among the few foods that provoke high blood sugar and insulin more than even our favorite grain to bash, wheat. It means that people who are gluten-free and consume such garbage replacement products gain weight in visceral inflamm...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates Detox gluten-free grain-free grains Inflammation Weight Loss Source Type: blogs
Abstract Chemical allergens are small molecules able to form a sensitizing complex once they bound to proteins. One of the most frequent manifestations of chemical allergy is contact hypersensitivity, which can have serious impact on quality of life. Allergic contact dermatitis is a predominantly CD8 + T cell-mediated immune disease, resulting in erythema and eczema. Chemical allergy is of considerable importance to the toxicologist, who has the responsibility of identifying and characterizing the allergenic potential of chemicals, and estimating the risk they pose to human health. This review aimed ...
Source: Archives of Toxicology - Category: Toxicology Authors: Tags: Arch Toxicol Source Type: research
Source: MayoClinic.com - Ask a Specialist - Category: Consumer Health News Source Type: news
Condition:   Moderate-to-severe Atopic Eczema Intervention:   Other: No study-specific intervention Sponsor:   Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Eczema;   Atopic Dermatitis;   Atopic Dermatitis and Related Conditions Interventions:   Other: Bubbles;   Other: Bleach and Bubbles Sponsor:   University of North Carolina, Chapel Hill Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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