New Kirkup report criticises regulators for failing to spot care scandal

Regulators and commissioners have been criticised by an independent review after it took four years to identify serious care failings at Liverpool Community Health Trust.
Source: HSJ - Category: UK Health Source Type: news

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We present a novel approach of laser plasma processing of silicon surface to fabricate SiNf thin films with diverse range of resistivity. Parallel plate electrode configuration was employed to measure the resistance offered by SiNf thin film fabricated using various laser parameters. Pulsation width of laser was varied to affect the plasma temperature causing variation in suitable ablation conditions. In addition, scanning parameter of leading(i.e.distance between two consecutive scan with laser beam) was modified to change the extent of silicon surface covered under direct laser gaussian beam causing variation in process ...
Source: Results in Physics - Category: Physics Source Type: research
Publication date: March 2019Source: Results in Physics, Volume 12Author(s): Dorina Kovács, János Dobránszky, Attila BonyárAbstractActive screen plasma nitriding (ASPN) was performed on tempered 42CrMo4 low alloy steel samples. The effects of two technological parameters, namely 1) the hole size of the screen and 2) the open area ratio were investigated on the properties of the developed nitride layer. Scanning electron microscopy (SEM), atomic force microscopy (AFM) and Vickers microhardness testing were used for the characterization of the surface. The thickness of the nitride layer, the microh...
Source: Results in Physics - Category: Physics Source Type: research
Publication date: April 2019Source: Fish &Shellfish Immunology, Volume 87Author(s): Tianqing Huang, Wei Gu, Bingqian Wang, Yuyong Zhang, Lili Cui, Zuochun Yao, Cheng Zhao, Gefeng XuAbstractHepcidin, a hepatic antimicrobial peptide, is a key player of the nonspecific immune system. The structure of hepcidin gene from brown trout (Bthepc) has been characterized at the molecular level. The 1158-bp mRNA generates a coding sequence (CDS) of 267 bp, which encodes an 88-amino acid protein. Molecular evolution analysis classified Bthepc to the family Salmonidae. Amino acid sequence homologies between Bthepc and hepcidin in oth...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
Conclusions We suggest that interventions to decrease the burden of late-life depression should be targeted at individuals that are affected by chronic somatic comorbidities and are limited in mental and physical functioning. Promotion of help-seeking of older adults, de-stigmatization of mental illness and education of general practitioners could help decrease the gap in mental health service utilization. PMID: 30658276 [PubMed - as supplied by publisher]
Source: Journal of the Association of European Psychiatrists - Category: Psychiatry Tags: Eur Psychiatry Source Type: research
Authors: Russo F, Manfredi M, Panebianco V, Armando E, De Luca S, Mazzetti S, Giannini V, Mele F, Bollito E, Appendino E, Regge D, Porpiglia F Abstract BACKGROUND: The knowledge of tumour location and extension can allow a modulated radical prostatectomy in order to minimize positive surgical margins and reduce functional morbidity after surgery in patients with prostate cancer (PCa). Multiparametric (mp) magnetic resonance imaging (MRI) could allow the assessment of tumour extension and of its relationship with external structures. Aim of this study is to propose a new radiological Wheeler (rW) staging system appl...
Source: Minerva Urologica e Nefrologica - Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
CONCLUSIONS: In oncological patients, despite its high detection rate, 18F-FDG PET/CT, as well as any other clinico-anatomical features, cannot distinguish whether a malignant solitary pulmonary nodule is a metachronous lung cancer or a metastasis, supporting the need of histological differential diagnosis. PMID: 30654605 [PubMed - as supplied by publisher]
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Tags: Q J Nucl Med Mol Imaging Source Type: research
Hit evaluation of an α-helical peptide: Ala-scan, truncation, and sidechain-to-sidechain macrocyclization of an RNA polymerase Inhibitor. Biol Chem. 2018 Dec 01;: Authors: Kamal AAM, Habib M, Haupenthal J, Hartmann RW, Empting M Abstract RNA polymerase (RNAP) remains a relatively underexplored target with only rifampicin and fidaxomicin in clinical use. Hence, the concurrent rise in bacterial resistance rate urges the search for novel RNAP inhibitors with novel mode of action. In this work, we investigated the impact of several systematic modifications including sidechain-to-sidechain macrocyliza...
Source: Biological Chemistry - Category: Chemistry Tags: Biol Chem Source Type: research
In a packed morning session in Llandudno’s Venue Cymru conference centre, UNISON’s Black members debated a wide range of important motions. Tanya Igbosi-McGee for the national Black members committee opened a major debate on the Windrush scandal. “It has been a nightmare – it really has,” she said, before listing several planned deportation flights in the future and others that happened ate last year. On each flight, each person being deported has “three guards assigned to them – more, if they feel you’re aggressive”. Yet even after apologising for the Windrush scandal,...
Source: UNISON meat hygiene - Category: Food Science Authors: Tags: Article News 2019 Black Members Conference disability discrimination LGBT Windrush Source Type: news
Publication date: March 2019Source: Microchemical Journal, Volume 145Author(s): Mehrnaz Ghoochian, Homayon Ahmad Panahi, Soheil Sobhanardakani, Lobat Taghavi, Amir Hessam HassaniAbstractIn this research, Fe3O4/SiO2 nanoparticles with core-shell morphology were fabricated through co-precipitation method and used in a new method for the preparation of poly (amidoamine) (PAMAM)-magnetite nanoparticles; Then their use in the immobilization of chitosan (Fe3O4/SiO2/Thermosensitive/PAMAM-CS nanoparticles) was investigated. In so doing, Fe3O4/SiO2/Thermosensitive/PAMAM-CS nanoparticles characterized by X-ray diffraction (XRD) spec...
Source: Microchemical Journal - Category: Chemistry Source Type: research
We see lots of patients who are misdiagnosed as having PCO (polycystic ovarian disease) , and this is partly because lots of sonographers aren't good at making the diagnosis properly.When they see a few ovarian follicles on an ultrasound scan, they interpret these as being small cysts, and any time they see a few cysts in the ovaries, they say that the patient has PCO.This is completely incorrect, because there are very strict criteria laid down for how to make a diagnosis of PCO on an ultrasound scan. The antral follicle count needs to be high; the ovaries need to be large; and the ovarian stroma needs to be increased. Un...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
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