Suprachoroidal shunts

This article reviews recent studies evaluating the efficacy and safety of ab externo and ab interno suprachoroidal shunts designed to augment uveoscleral outflow in patients with open angle glaucoma. Recent findings The Gold Shunt and STARflo are placed into the suprachoroidal space via an ab externo approach, while the CyPass Micro-Stent and iStent Supra are inserted ab interno through a clear corneal incision. A small randomized clinical trial suggested similar efficacy among two different models of the Gold Shunt and the Ahmed glaucoma valve. The pivotal multicenter, randomized COMPASS trial showed that the CyPass Micro-Stent combined with cataract surgery is more effective than cataract surgery alone through 2 years. Study results suggest a favorable safety profile for each suprachoroidal device and intraocular pressure-lowering to the mid-to-high teens with an associated reduction in medication burden. Given the relative novelty of these procedures, it is currently unknown whether fibroblastic proliferation within the suprachoroidal space may limit their long-term success. Summary Renewed interest in the suprachoroidal space has led to the development of new biocompatible glaucoma implants. Ab interno devices are easily combined with cataract surgery and preserve conjunctiva for future incisional glaucoma surgery. Additional data regarding the long-term efficacy and late complications of suprachoroidal shunts are needed.
Source: Current Opinion in Ophthalmology - Category: Opthalmology Tags: GLAUCOMA: Edited by Donald L. Budenz Source Type: research

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Ten-year incidence of primary angle closure in elderly Chinese: the Liwan Eye Study. Br J Ophthalmol. 2018 May 18;: Authors: Wang L, Huang W, Huang S, Zhang J, Guo X, Friedman DS, Foster PJ, He M Abstract PURPOSE: To determine the 10-year incidence of all forms of primary angle closure (PAC) in phakic eyes and its risk factors in an urban Chinese population aged 50 years and older. METHODS: Survivors of 1405 baseline participants were invited to attend the 10-year follow-up visit in the Liwan Eye Study. Participants with established baseline angle closure, including primary angle...
Source: The British Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Br J Ophthalmol Source Type: research
CONCLUSION: Main result of this survey was the specification of serious bleeding complications which are permanent vision loss and re-operation. They could serve as endpoint parameters for essential future investigations. Nevertheless, this survey makes clear that the decision about an adjustment of anticoagulant medication in ophthalmic surgery is currently made individually and not based on established standards. PMID: 29770858 [PubMed - as supplied by publisher]
Source: Der Ophthalmologe - Category: Opthalmology Authors: Tags: Ophthalmologe Source Type: research
Were The Graduate's Ben Braddock to receive a one-word bit of career advice today, it might very well be "MIGS" instead of plastics. MIGS stands for minimally invasive glaucoma surgery, and both financial analysts and developers of the tiny devices designed to treat the disease expect the market to pop for the foreseeable future. "On a scale of one through 10, I would say the market is probably somewhere between one and two in terms of maturity," said Dave Van Meter, CEO of Irvine, CA-based Ivantis. "The market in the U.S. today is probably somewhere around a couple hundred million dollars, ac...
Source: MDDI - Category: Medical Devices Authors: Tags: Implants Source Type: news
Authors: Doycheva D, Deuter C, Grajewski R Abstract Topical corticosteroids are effective anti-inflammatory drugs in the treatment of anterior uveitis. The intraocular efficacy of topical corticosteroids mostly depends on their intraocular permeability through the cornea. Lipophile derivatives such as dexamethasone and prednisolone acetate penetrate better into the anterior chamber than hydrophilic derivatives. Prednisolone acetate 1% is the first choice in the therapy of patients with anterior uveitis. Loteprednole and fluorometholone have a slightly weaker anti-inflammatory effect, but they induce less elevation ...
Source: Klinische Monatsblatter fur Augenheilkunde - Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research
Abstract PURPOSE: To evaluate the feasibility, efficacy and safety of Ex-PRESS implantation combined with phacoemulsification surgery in primary angle-closure glaucoma (PACG) with cataract. MATERIALS AND METHODS: This is a prospective, nonrandomized study. A total of 34 eyes of 34 subjects were enrolled. The assessments were conducted preoperatively and postoperatively at 1 week and 1, 3, 6, 12, 18, 24, 30, 36 months. The assessments included intraocular pressure (IOP), best corrected visual acuity (BCVA), the number of glaucoma medications, corneal endothelial cell density (ECD) and related complic...
Source: Current Eye Research - Category: Opthalmology Authors: Tags: Curr Eye Res Source Type: research
Conclusions: To the best of our knowledge this is the largest study that has investigated the association between postoperative topical PGA or topical beta-blocker use and the incidence of pseudophakic CME. Postoperative use of both topical PGAs and topical beta-blockers was found to be associated with the incidence of pseudophakic CME.
Source: Journal of Glaucoma - Category: Opthalmology Tags: Original Studies Source Type: research
To report the long-term efficacy of endoscopic cyclophotocoagulation (ECP) in pediatric glaucoma following cataract surgery (GFCS).
Source: Journal of AAPOS - Category: Opthalmology Authors: Tags: Major Article Source Type: research
Authors: Ambroz SC, Töteberg-Harms M, Hanson JVM, Funk J, Barthelmes D, Gerth-Kahlert C Abstract Purpose: To determine and to analyze the outcome of pediatric cataract surgery. Methods: A retrospective chart review of individuals aged up to 10 years who underwent cataract surgery between January 1, 2004, and December 31, 2014, at the UniversityHospital Zurich, Switzerland. Results: 63 children (94 affected eyes) with bilateral (68/94) or unilateral (26/94) cataract were identified. Surgery was performed at a median age of 1.5 months (IQR: 1.3-2.6 months) for the aphakic group (45/94) and of 50.7 months...
Source: Journal of Ophthalmology - Category: Opthalmology Tags: J Ophthalmol Source Type: research
Johnson &Johnson (NYSE:JNJ) saw its vision care sales grow 34% last quarter over its previous first quarter as it looks to significantly grow the business into the surgical and device segments, according to a CNBC report. The company added a number of surgical products alongside a contact subscription service, which come in addition to its existing popular Acuvue contact lens line, according to the report. The investment has seen a significant return for the company, becoming one of its fastest-growing platforms. Johnson &Johnson only began investing in eye surgery two years ago after announcing it would acqui...
Source: Mass Device - Category: Medical Devices Authors: Tags: Business/Financial News Optical/Ophthalmic Wall Street Beat johnsonandjohnson Source Type: news
CONCLUSIONS: Patients with high hyperopia often have ocular comorbidities. Such eyes may be surgically challenging, resulting in reduced benefits from cataract surgery compared to normal eyes. PMID: 29669369 [PubMed - in process]
Source: Klinische Monatsblatter fur Augenheilkunde - Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research
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