Should coffee come with a cancer warning?
Coffee shops are being sued under California's Proposition 65 which requires businesses to alert consumers about cancer-causing chemicals
Authors: Schuler PJ, von Witzleben A, Doescher J, Wollenberg B, Dietz A, Hoffmann TK Abstract In recent years, immunotherapy has been shown to be a promising approach for the treatment of various tumor entities. Due to further pharmacological developments and new studies, the checkpoint inhibitors have now arrived in the clinic. To date, patients with cancers in the head and neck region have benefited from these agents as part of a palliative therapy. Current clinical trials are testing other indications for the checkpoint inhibitors as monotherapy or in combination with other therapeutic approaches. The ...
ConclusionsA small subset of pulmonary adenocarcinomas shows immunoreactivity for ER clones 6F11 and 1D5 in FNA samples (18.2% and 9.1%, respectively). The absence of immunoreactivity for ER‐SP1 clone indicates higher specificity of this clone in non‐breast tissue. The differential diagnostic value of all ER clones in malignant PEs appears to be secure. Larger studies are necessary to validate this observation.
Mari Lopez, who ran the food channel at home in Houston, Texas with her niece Liz Johnson, told viewers she had rejected traditional treatment for breast cancer in favor of a 90-day juice cleanse.
No abstract available
Conclusions: Lenvatinib is an effective treatment and may improve the prognosis of unresectable ATC. Four of the 5 patients had hypothyroidism, which may have been associated with treatment-induced injury of the thyroid gland. There were many treatment-related adverse effects, most of which were manageable by dose modification and medical therapy.Eur Thyroid J
Both AHN and UPMC, the two big health care providers in the Pittsburgh region, are putting more emphasis on community care, offering sophisticated treatment previously available at big-city hospitals.
CONCLUSIONS: Our results confirm the prognostic significance of PD-L1 expression in thyroid cancer patients. PD-L1 expression has the potential to be implemented as a prognostic biomarker used to guide clinicians in identifying patients with more aggressive cancers, and for the selection of individuals that would derive durable clinical benefit from anti-PD-1/PD-L1 immunotherapy. Prospective clinical trials will be useful to support these findings. PMID: 29455638 [PubMed - as supplied by publisher]
Abstract T and B lymphocytes are key players of the adaptive immune system. They recognize pathogenic cues via the T cell antigen receptor (TCR) and the B cell antigen receptor (BCR) to get activated and execute their protective function. TCR and BCR signaling are initiated at the plasma membrane and subsequently propagated into the cell, ultimately leading to cell activation and a protective immune response. However, inappropriate activation of T and B cells can be detrimental to the host resulting in autoimmune disorders, immunodeficiencies, and cancer. The TCR and BCR are located at the plasma membrane, which c...