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Why Do Wounds Itch?

Why Do Wounds Itch? Wounds. 2018 Jan;30(1):1-3 Authors: Lerner E Abstract Everyone has experienced itch. It might simply be the nuisance of a mosquito bite or a transient itch on the scalp that is relieved by a simple scratch. For wounds such as venous ulcers, itch may be present but is usually mild. For some of the 40% of people with neuropathic itch or pain that can develop and persist following mastectomy, itch can be overwhelming, intractable, not widely appreciated by the medical community, and poorly responsive to current treatment regimens. Why are some wounds in some patients itchy whereas seemingly equivalent ones in the same or other patients not? Why is the sensation of itch present in the wound itself in some cases while in the surrounding skin in others? Why are burns so frequently associated with itch? How commonly do wounds itch? Detailed answers to these questions are lacking, but this area is beginning to be explored. Herein, the author provides an overview of the current understanding of the physiology of itch. An effort is made to place that understanding in the context of wounds, and therapeutic approaches that may be outside of the conventional toolkit are made based on this background. PMID: 29406291 [PubMed - in process]
Source: Wounds - Category: General Medicine Tags: Wounds Source Type: research

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Authors: Bolton LT Abstract Dear Readers, Itching (pruritus) of a wound, scar, or dermatologic disorder can negatively impact a patient's quality of life, resulting in injurious scratching1 or impeded rehabilitation.2 Like pain, itch can cause the su erer to lose sleep and appetite or even consider suicide.3,4 Clinical measures of pruritus have proved reliable and valid in individuals with burn wounds, dermatologic conditions, or urticaria5-7 or resulting scars,2 allowing studies to clarify its impact on human experience and compare the e ects of interventions to reduce itching. This Evidence Corner explores the e ...
Source: Wounds - Category: General Medicine Tags: Wounds Source Type: research
Abstract AbstractMore than half of individuals experiencing major thermal burn injury (MThBI) receive an autologous skin graft (autograft), in which skin is removed from a healthy “donor” site and transplanted to the burn site. Persistent pain and itch at the graft site are major causes of suffering and disability in MThBI survivors. African Americans have a higher risk of MThBI, and in other clinical settings African Americans experience a greater burden of pain and itch relative to European Americans. However, to our knowledge, ethnic differences in skin graft site pain and itch outcomes after MThBI have not ...
Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research
CONCLUSION: The combination of apremilast with NB-UVB was effective for the treatment of moderate to severe plaque psoriasis, without any unexpected safety signals. Apremilast combined with NB-UVB provided a high treatment response in patients with moderate to severe plaque psoriasis, and may be an option for patients to enhance a patient's initial therapeutic response. J Drugs Dermatol. 2017;16(10):957-962.. PMID: 29036248 [PubMed - in process]
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
Larry Burrows was a seasoned veteran of the Vietnam War when, in early 1968, he met 12-year-old Nguyễn Thị Tròn. Operating out of Saigon, the southern Republic of Vietnam’s capital, the photographer had been covering the conflict for LIFE magazine since 1962. He shadowed American troops, documenting ferocious firefights, surviving hours in the air with helicopter-gunship crews, and freeze-framing harrowing moments of bravery and despair, exhaustion, and appalling violence in combat zones. Though much of his best work had been shot in the thick of the action, he had come to be haunted by the trauma visited ...
Source: TIME.com: Top Science and Health Stories - Category: Consumer Health News Authors: Tags: Uncategorized Larry Burrows LIFE Magazine photography Vietnam Vietnam War Source Type: news
Over half of individuals experiencing major thermal burn injury (MThBI) receive an autologous skin graft (autograft), in which skin is removed from a healthy " donor " site and transplanted to the burn site. Persistent pain/itch at the graft site are major causes of suffering and disability in MThBI survivors. African Americans have a higher risk of MThBI, and in other clinical settings African Americans experience a greater burden of pain and itch relative to European Americans. However, to our knowledge, ethnic differences in skin graft site pain/itch outcomes after MThBI have not been assessed. We evaluated sk...
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
Objective: Pain and itch symptoms are common after major thermal burn injury (MThBI)—requiring tissue autografting. To our knowledge, no prospective longitudinal studies have characterized pain and itch outcomes after tissue autografting and associations between and functional interference caused by such symptoms. Materials and Methods: We prospectively evaluated burn graft site and tissue donor site pain and itch severity (0 to 10, numeric rating scale) over 1 year among a representative cohort of MThBI survivors (n=96) who received tissue autografting within 14 days of MThBI. Results: Nearly all participants had ...
Source: The Clinical Journal of Pain - Category: Anesthesiology Tags: Original Articles Source Type: research
Restorative sleep is an important component of quality of life. Disturbances in sleep after burn injury were reported but all based on uncontrolled or nonstandardized data. The occurrence and the effect of long-term sleep problems in young adult burn survivors have not been well defined. This 5-year (2003–2008) prospective multicenter longitudinal study included adults with burn injuries ages 19 to 30 years who completed the Young Adult Burn Outcome Questionnaire (YABOQ) up to 36 months after injury. The items measured 15 patient-reported outcomes including physical, psychological, and social statuses and symptoms su...
Source: Journal of Burn Care and Research - Category: Rehabilitation Tags: Original Articles Source Type: research
AbstractWe assessed the long-term effects of pulsed high-intensity laser therapy (HILT) in post-burn pruritus treatment. A total of 49 adult burn patients with mean age of 31.53  ± 10.14 years participated, with 24 patients randomly assigned to the active laser group (ALG) and 25 in the placebo laser group (PLG). The ALG received HILT three times per week for 6 weeks, while the PLG received placebo HILT. Both groups received 10-mg cetirizine tablets twice daily and 1 0 mg at bedtime. All patients were advised to massage their burn scars with coconut oil for 5 min four times daily. T...
Source: Lasers in Medical Science - Category: Laser Surgery Source Type: research
DiscussionResults of this study will determine the effectiveness of three noninvasive scar interventions in children at risk of, and with, scarring post burn or post reconstruction.Trial registrationAustralian New Zealand Clinical Trials Registry,ACTRN12616001100482. Registered on 5 August 2016.
Source: Trials - Category: Research Source Type: clinical trials
Authors: Foroutan N, Nikvarz N Abstract Pruritus can be one of the distressing symptoms of many dermatologic, systemic, neurologic or psychiatric disorders. In each case, the origin of itch is in the skin and/or the nervous system. Involvement of the nervous system causes neurogenic, psychogenic or neuropathic itch. Itch sensation is transferred to the central nervous system via unmyelinated C-type nerve fibers, and many mediators and receptors engage in the its induction and transmission. Also it has been demonstrated that there are similarities and interactions between neurotransmitters and pathways of pain and i...
Source: Journal of Pharmacy and Pharmaceutical Sciences - Category: Drugs & Pharmacology Tags: J Pharm Pharm Sci Source Type: research
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