Why Do Wounds Itch?

Why Do Wounds Itch? Wounds. 2018 Jan;30(1):1-3 Authors: Lerner E Abstract Everyone has experienced itch. It might simply be the nuisance of a mosquito bite or a transient itch on the scalp that is relieved by a simple scratch. For wounds such as venous ulcers, itch may be present but is usually mild. For some of the 40% of people with neuropathic itch or pain that can develop and persist following mastectomy, itch can be overwhelming, intractable, not widely appreciated by the medical community, and poorly responsive to current treatment regimens. Why are some wounds in some patients itchy whereas seemingly equivalent ones in the same or other patients not? Why is the sensation of itch present in the wound itself in some cases while in the surrounding skin in others? Why are burns so frequently associated with itch? How commonly do wounds itch? Detailed answers to these questions are lacking, but this area is beginning to be explored. Herein, the author provides an overview of the current understanding of the physiology of itch. An effort is made to place that understanding in the context of wounds, and therapeutic approaches that may be outside of the conventional toolkit are made based on this background. PMID: 29406291 [PubMed - in process]
Source: Wounds - Category: General Medicine Tags: Wounds Source Type: research

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Publication date: Available online 30 July 2018Source: BurnsAuthor(s): Vetrichevvel Palanivelu, Siaavash Maghami, Hilary J. Wallace, Dulharie Wijeratne, Fiona M. Wood, Mark W. FearAbstractBurn scars can be associated with significant loss of cutaneous sensation, paresthesia and chronic pain. Long-term systemic changes in cutaneous innervation may contribute to these symptoms and dorsal root ganglia have been implicated in the development of chronic neuropathic pain. Therefore we hypothesized that changes in cutaneous innervation after burn injury may be mediated at the level of the dorsal root ganglia. Burn group rats (n&n...
Source: Burns - Category: Dermatology Source Type: research
This study aimed to examine the maturation trajectory of post-burn hypertrophic scars in a 6-month monitored pressure therapy intervention programme and investigate the difference in the trajectory between patients receiving early intervention and patients receiving late intervention.MethodsThirty-four patients with sixty-five post-burn hypertrophic scar samples were recruited for the study. All the subjects were treated with a 6-month pressure therapy programme with the pressure dosage regulated using a newly developed pressure therapy system, the Smart Pressure Monitored Suits. The selected scars were assessed with MiniS...
Source: Burns - Category: Dermatology Source Type: research
If you have mesothelioma and you’ve already received standard-of-care therapies, you may be considering an immunotherapy clinical trial. If you’re considering this option, a free immunotherapy teleconference is a great place to learn more. CancerCare recently hosted two one-hour education workshops featuring panels of immunotherapy experts. Part I of the teleconference presented an overview of immunotherapy. Part II of the teleconference, which is available online for free, focused exclusively on immunotherapy side effects. Understanding these issues and the role each patient plays in managing their own side ef...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
Conclusion Cold pack therapy, a non-invasive, non-pharmacological treatment modality significantly reduces post-burn pruritus and could be useful in burn patients.
Source: Burns - Category: Dermatology Source Type: research
Conclusions: A larger proportion of women whose MBS improved had a Lactobacillus dominant microbiota at enrollment than those who had no improvement during the trial, though this difference was not statistically significant. Larger trials are needed to determine whether vaginal microbiota modify or mediate treatment responses in women with GSM.
Source: Menopause - Category: OBGYN Tags: Original Articles Source Type: research
Stefano had been complaining recently (last week) about a strange sort of pain/ache in his back that began more or less last Wednesday. We thought he’d pulled a muscle or some such thing. But the pain wasn’t going away. When he’d come home from work, and in the morning when he got out of bed, it was ouch-ouch-ouch. I suggested he at least call our GP, but he didn’t want to bother him. He really thought it was a pulled muscle. Then, on Saturday morning, he asked me to take a look. I found a little rash on the left side of his torso, but he said it wasn’t where the pain was. And so I didn’...
Source: Margaret's Corner - Category: Cancer & Oncology Authors: Tags: Blogroll shingles turmeric paste Source Type: blogs
Authors: Bolton LT Abstract Dear Readers, Itching (pruritus) of a wound, scar, or dermatologic disorder can negatively impact a patient's quality of life, resulting in injurious scratching1 or impeded rehabilitation.2 Like pain, itch can cause the su erer to lose sleep and appetite or even consider suicide.3,4 Clinical measures of pruritus have proved reliable and valid in individuals with burn wounds, dermatologic conditions, or urticaria5-7 or resulting scars,2 allowing studies to clarify its impact on human experience and compare the e ects of interventions to reduce itching. This Evidence Corner explores the e ...
Source: Wounds - Category: General Medicine Tags: Wounds Source Type: research
Abstract AbstractMore than half of individuals experiencing major thermal burn injury (MThBI) receive an autologous skin graft (autograft), in which skin is removed from a healthy “donor” site and transplanted to the burn site. Persistent pain and itch at the graft site are major causes of suffering and disability in MThBI survivors. African Americans have a higher risk of MThBI, and in other clinical settings African Americans experience a greater burden of pain and itch relative to European Americans. However, to our knowledge, ethnic differences in skin graft site pain and itch outcomes after MThBI have not ...
Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research
CONCLUSION: The combination of apremilast with NB-UVB was effective for the treatment of moderate to severe plaque psoriasis, without any unexpected safety signals. Apremilast combined with NB-UVB provided a high treatment response in patients with moderate to severe plaque psoriasis, and may be an option for patients to enhance a patient's initial therapeutic response. J Drugs Dermatol. 2017;16(10):957-962.. PMID: 29036248 [PubMed - in process]
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
Larry Burrows was a seasoned veteran of the Vietnam War when, in early 1968, he met 12-year-old Nguyễn Thị Tròn. Operating out of Saigon, the southern Republic of Vietnam’s capital, the photographer had been covering the conflict for LIFE magazine since 1962. He shadowed American troops, documenting ferocious firefights, surviving hours in the air with helicopter-gunship crews, and freeze-framing harrowing moments of bravery and despair, exhaustion, and appalling violence in combat zones. Though much of his best work had been shot in the thick of the action, he had come to be haunted by the trauma visited ...
Source: TIME.com: Top Science and Health Stories - Category: Consumer Health News Authors: Tags: Uncategorized Larry Burrows LIFE Magazine photography Vietnam Vietnam War Source Type: news
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