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Synchronization of intrinsic 0.1 ‐Hz blood‐oxygen‐level‐dependent oscillations in amygdala and prefrontal cortex in subjects with increased state anxiety

In this study, we report on two different approaches: first, on computing the phase‐locking value in the frequency band 0.07–0.13 Hz between heart beat‐to‐beat interval (RRI) and BOLD oscillations and second, between multiple BOLD oscillations (functional connectivity) in four resting states in 23 scanner‐naïve, anxious healthy subjects. The first method revealed that vascular 0.1‐Hz BOLD oscillations preceded those in RRI signals by 1.7 ± 0.6 s and neural BOLD oscillations lagged RRI oscillations by 0.8 ± 0.5 s. Together, vascular BOLD oscillations preceded neural BOLD oscillations by ~90° or ~2.5 s. To verify this discrimination, connectivity patterns of neural and vascular 0.1‐Hz BOLD oscillations were compared in 26 regions involved in processing of emotions. Neural BOLD oscillations revealed significant phase‐coupling between amygdala and medial frontal cortex, while vascular BOLD oscillations showed highly significant phase‐coupling between amygdala and multiple regions in the supply areas of the anterior and medial cerebral arteries. This suggests that not only slow neural and vascular BOLD oscillations can be dissociated but also that two strategies may exist to optimize regulation of anxiety, that is increased functional connectivity between amygdala and medial frontal cortex, and increased cerebral blood flow in amygdala and related structures. Slow spontaneous BOLD oscillations at...
Source: European Journal of Neuroscience - Category: Neuroscience Authors: Tags: Research Report Source Type: research

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In this study, the effects of anxiety chemosignals on the performance of dental students operating on simulation units, wearing t-shirts imbued with human sweat and masked with eugenol were tested. Twenty-four 4th year dental students (17F) donated their body odors in two sessions (Anxiety and Rest). Twenty-four normosmic, sex- and age-matched test subjects who were3rd year dental students performed three dental procedures while smelling masked anxiety body odors, masked rest body odors or masker alone. The intensity and pleasantness ratings showed that the test subjects could not report perceptual differences between the ...
Source: Chemical Senses - Category: Biochemistry Authors: Tags: Chem Senses Source Type: research
CONCLUSIONS: Findings of hyperconnectivity stemming from the precuneus and hypoconnectivity from the PCC may reflect maladaptive self-reflection and mentalization. However, additional investigation is warranted to further clarify these relationships. PMID: 29756354 [PubMed - as supplied by publisher]
Source: Suicide and Life-Threatening Behavior - Category: Psychiatry & Psychology Authors: Tags: Suicide Life Threat Behav Source Type: research
Conclusion: Findings of the present study validate the concept of "mix headache" and explains the clinical observation that chronic daily headache (CDH) patients responds better with a combination of anti-migraine and anti-stress medications. PMID: 29736067 [PubMed]
Source: Indian Journal of Psychiatry - Category: Psychiatry Tags: Indian J Psychiatry Source Type: research
Lots of IVF doctors are very trigger happy, and make a diagnosis which is completely inaccurate. For example, they will do an ultrasound scan for a patient on the fifth or sixth day of the cycle and notice at that time that the follicles are small or the endometrium is thin , and then tell her, "Oh, your thin endometrium means that you most probably have endometrial tuberculosis, and you need investigation and treatment for this." This is plainly ridiculous ! On Day 6, most fertile women will have small follicles , because they haven't started growing yet , as a result of which their estrogen levels are goin...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Tags: IVF diagnosis IVF misdiagnosis IVF overdiagnosis IVF tests Source Type: blogs
Technology and mental well-being might seem as profoundly antagonistic expressions. However, there are excellent digital tools to reach mindfulness and to practice meditation. You can even use these smartphone apps, virtual reality solutions, digital devices as de-stressing and de-toxifying means for getting out of technology – as, after a while, you will be able to practice all types of anti-anxiety skills on your own. So, let The Medical Futurist show you how you can enhance your mental and emotional health with technology. The need for taking care of our emotional health “Just as we observe physical hygiene ...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: From Chance to Choice Health Sensors & Trackers anxiety depression digital health emotional emotional health Innovation mental health mental wellbeing stress management technology Source Type: blogs
It may seem like stress is an external force — something that happens to you, such as a rude driver, a work deadline, or the illness of a loved one. As a result, it may seem like there’s really nothing you can do about your stress, but this simply isn’t the case. You may not be able to shape the world so that nothing stressful ever happens to you again, but you can change the way you respond to stress, and that can make all the difference in how you feel.   The most fundamental thing to understand about stress is that it isn’t a one-time event with one cause and one reaction. It’s actuall...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Habits Happiness LifeHelper Motivation and Inspiration Self-Help Stress Coping Skills Cortisol fight or flight homeostatis neuroception Reactivity Self Medication Stress Hormone stress reduction Stress Response Sympathetic Source Type: blogs
Vaginal ultrasound is an extremely useful tool when evaluating an infertile woman, but it often bothers me because there are some sonographers who over interpret the scan images. Now, I like the fact that they are careful and systematic, and document everything they see by taking lots of images. However, I hate the fact that draw clinical conclusions based on the black and white images they see on the screen - and they shouldn't be doing this.Their reports will say things like, " There are adhesions between the ovary and the uterus"; " There is a 3 cm endometriotic cyst"; the fallopian tubes a...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
Scanxiety, the anxiety/stress associated with an imaging test, has never been evaluated in relation to coronary CT angiography (Coronary CTA). As it could impact heart rate and thereby affect image quality of Coronary CTA, we aimed to evaluate the prevalence, severity, and impact of scanxiety on quality and interpretability of Coronary CTA.
Source: Journal of Cardiovascular Computed Tomography - Category: Radiology Authors: Tags: Research paper Source Type: research
This study set out to examine amechanism that activates the attentional network in the salience region of the brain.The results offer a new way to approach anxiety, depression and agitation in patients with dementia.Learn More -Alzheimer's Care Anger, Frustration, and AgitationActivation of neighboring regions of the brain may also offer opportunities to delay the continued decline caused by the disease.The StudyFor three weeks, the researchers helped participants select meaningful songs and trained the patient and caregiver on how to use a portable media player loaded with the self-selected collection of music.“When...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: Alzheimer's disease Alzheimer's Patients brain health memory music research science Source Type: blogs
CONCLUSIONS: Moderate alcohol consumption is associated with a lower risk of type 2 diabetes, after adjusting for HED, health and lifestyle, and psychosocial characteristics. The association was inverse but non-significant after adjusting for socioeconomic factors. When stratified by occupational position, there was an inverse association only in those with low occupational position and after adjusting for low job control. PMID: 29734853 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Public Health - Category: International Medicine & Public Health Authors: Tags: Scand J Public Health Source Type: research
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