Synchronization of intrinsic 0.1 ‐Hz blood‐oxygen‐level‐dependent oscillations in amygdala and prefrontal cortex in subjects with increased state anxiety

In this study, we report on two different approaches: first, on computing the phase‐locking value in the frequency band 0.07–0.13 Hz between heart beat‐to‐beat interval (RRI) and BOLD oscillations and second, between multiple BOLD oscillations (functional connectivity) in four resting states in 23 scanner‐naïve, anxious healthy subjects. The first method revealed that vascular 0.1‐Hz BOLD oscillations preceded those in RRI signals by 1.7 ± 0.6 s and neural BOLD oscillations lagged RRI oscillations by 0.8 ± 0.5 s. Together, vascular BOLD oscillations preceded neural BOLD oscillations by ~90° or ~2.5 s. To verify this discrimination, connectivity patterns of neural and vascular 0.1‐Hz BOLD oscillations were compared in 26 regions involved in processing of emotions. Neural BOLD oscillations revealed significant phase‐coupling between amygdala and medial frontal cortex, while vascular BOLD oscillations showed highly significant phase‐coupling between amygdala and multiple regions in the supply areas of the anterior and medial cerebral arteries. This suggests that not only slow neural and vascular BOLD oscillations can be dissociated but also that two strategies may exist to optimize regulation of anxiety, that is increased functional connectivity between amygdala and medial frontal cortex, and increased cerebral blood flow in amygdala and related structures. Slow spontaneous BOLD oscillations at...
Source: European Journal of Neuroscience - Category: Neuroscience Authors: Tags: Research Report Source Type: research

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Anxiety occasionally visits us all. When we give an important presentation, take a test, go on a first date or walk down a dark alley our minds and bodies naturally respond by going on high alert and attuning to the potential dangers and risks of these endeavors. A healthy amount of anxiety prevents us from falling victim to those dangers and risks. Choosing not to go down that dark alley could be a life-saving response. But an excessive amount of anxiety can increase our risk of suffering negative consequences. The millions of people who suffer from social anxiety disorder, panic disorder, post-traumatic stress disorder...
Source: Psych Central - Category: Psychiatry Authors: Tags: Anxiety Creativity Amygdala Humor Laughter Neuroscience Source Type: news
It’s tempting. I’ve been there. You hit a rough patch with your psychiatrist and you think, “I’m outta here.” There may be some things you can do to not only get your relationship back on track but also give it a turbo boost. I want to explore just a few of the things we can do to improve our relationships with our doctors. First some basic facts. Psychiatry is a rare discipline of medicine and the population of psychiatrists is aging and not being replaced quickly enough by younger physicians. There are many areas of the country, small town and rural particularly, that have few to no psychiat...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Bipolar Communication Personal Psychotherapy PTSD Schizophrenia Psychiatry Source Type: blogs
This study (i) evaluates the levels of ethical judgement, mental health, motivation, and self-compassion in 144 UK business students and (ii) assesses the relationships between these variables. A high proportion of respondents (i) believed that other students would behave unethically, whilst they themselves would not, and (ii) had a high level of anxiety, extrinsic motivation and self-compassion. Extrinsic motivation was associated with participants ’ belief that others would behave unethically, whilst intrinsic motivation was associated with strict ethical judgement and self-compassion. Extrinsic motivation and self...
Source: International Journal of Mental Health and Addiction - Category: Addiction Source Type: research
ConclusionThis case report highlights that elective surgery in patients living in rural area with history of recurrence PSP can lead to post-operative complications as bleeding or prolonged air leaks following the lysis of multiple pleural adhesions
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Are you stressed and tormented by your thoughts, again? Even when they are benign, the spinning and sheer pace of them affronts your brain’s processing center. And there is no escape from the onslaught. Most of us have been there. Sometimes it’s not so easy to slow things down or even take a full breath between those racing thoughts. What can you do to calm down and stop the “runaway train”? Sometimes the only option is to temporarily engage in something that grabs your attention. Netflix, a walk, doing a body scan, preparing a meal, or — my favorite — playing online scrabble. When...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Habits Memory and Perception Mindfulness adaptive self anxiety Authentic Self Breathing Exercise self-compassion Toxic thoughts Source Type: blogs
ConclusionOur results showed widespread alterations in pain thresholds in women with persistent pelvic pain that are indicative of central sensitization and a time ‐dependent correlation. Women with pelvic pain and suspicion of endometriosis should probably be treated more thoroughly in order to prevent or at least minimize the concomitant development of central sensitization.This article is protected by copyright. All rights reserved.
Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: Original Research Article Source Type: research
ConclusionsOffspring diet, but not prenatal maternal diet, affected a wide range of behaviors in these mice.
Source: Journal of Diabetes and Metabolic Disorders - Category: Endocrinology Source Type: research
Eating disorders are biologically based brain illnesses influenced by environmental and psychological factors. Environmental risk factors for developing an eating disorder include weight and appearance pressures, media messaging, and weight bullying. Biological factors include dieting/food exposure, genetics, neurochemistry, neurobiology, and hormones (notably estrogen). Psychological factors include stress, life transitions, identity, trauma, anxiety, depression, and substance use. While risk factors predispose certain individuals to eating disorders, precipitating factors such as significantly altering how one eats or s...
Source: Psych Central - Category: Psychiatry Authors: Tags: Anorexia Binge Eating Bulimia Bullying Children and Teens Eating Disorders Neuroscience Psychology Women's Issues Body Dysmorphia Body Image bulimia. food addiction Source Type: news
Introduction:The role of surveillance imaging in diffuse large B-cell lymphoma (DLBCL) after treatment with curative intent is debated. In 2013, the American Society of Hematology (ASH) Choosing Wisely® campaign (Hicks LK, et al. Blood 2013) released a recommendation to "limit surveillance CT scans in asymptomatic patients following curative-intent treatment for aggressive lymphoma." This was based on previous studies demonstrating a lack of survival benefit as well as a significant impact on the patient in terms of cost, anxiety, incidental findings and radiation exposure. Similar findings have been describe...
Source: Blood - Category: Hematology Authors: Tags: 902. Health Services Research-Malignant Diseases: Overuse, Costs, and Utilization of Health Services Source Type: research
ConclusionsNeuroticism was associated with higher utilization of publicly financed antenatal care in obstetric low ‐risk women, even after adjusting for predisposing and need factors. Future studies should address the benefits of interventions as a complement to routine antenatal care programs to reduce subclinical anxiety.This article is protected by copyright. All rights reserved.
Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: Original Research Article Source Type: research
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