Tanzania:Cancer Alarm As Number of New Cases Skyrockets

[Daily News] Moshi -THERE is an alarming upward trend in the number of people diagnosed with cancer, as a Northern Zone referral hospital attended to 3,450 patients against the target of 600 patients.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news

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Authors: Kim JW Abstract There have been many advances in endoscopic imaging technologies. Magnifying endoscopy with narrow-band imaging is an innovative optical technology that enables the precise discrimination of structural changes on the mucosal surface. Several studies have demonstrated its usefulness and superiority for tumor detection and differential diagnosis in the stomach as compared with conventional endoscopy. Furthermore, magnifying endoscopy with narrow-band imaging has the potential to predict the invasion depth and tumor margins during gastric endoscopic submucosal dissection. Classifications of th...
Source: Clinical Endoscopy - Category: Gastroenterology Tags: Clin Endosc Source Type: research
I have long argued that reduction in average telomere length with age is a downstream measure of aging, not an upstream cause of aging. Telomeres are the caps of repeated DNA sequences found at the end of chromosomes. A little is lost with each cell division, and when telomeres get too short then the cell become senescent and is destroyed. This mechanism limits the number of times a cell can replicate. The vast majority of our cells are somatic cells that are limited in this way. A tiny number of stem cells can maintain lengthy telomeres via use of the telomerase enzyme and thus divide indefinitely. This is how near all mu...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
Zellweger spectrum disorders (ZSDs) are a subgroup of peroxisomal biogenesis disorders with a generalized defect in peroxisome function. Liver disease in ZSDs has been associated with the lack of peroxisomal β-oxidation of C27-bile acid intermediates to form primary C24-bile acids, which prevents normal physiologic feedback and leads to accumulation of hepatotoxic bile acid intermediates. Primary bile acid therapy, oral cholic acid (CA), as adjunctive treatment for ZSDs, restores physiologic feedback inhibition on bile acid synthesis and inhibits formation of hepatotoxic bile acid intermediates. Our patient is a Cauca...
Source: Case Reports in Gastroenterology - Category: Gastroenterology Source Type: research
An amazing new PET/CT scanner has produced its first images of human subjects, giving scientists and clinicians new opportunities to treat cancer and other diseases. The EXPLORER is a high sensitivity total-body positron emission tomography scanner d...
Source: Medgadget - Category: Medical Devices Authors: Tags: Nuclear Medicine Oncology Radiation Oncology Radiology Surgery Source Type: blogs
ConclusionEEC inhibited the proliferation of SGC-7901 cells by inducing caspase-dependent apoptosis, arresting the cell cycle in the S phase and increasing endoplasmic reticulum stress. This study revealed that C. cicadae is a potential natural source of anticancer drugs.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Publication date: February 2019Source: Biomedicine &Pharmacotherapy, Volume 110Author(s): Feixue Xu, Xiaoqiang Si, Jing Wang, Aihong Yang, Tiansheng Qin, Yongxiu YangAbstractNectin-3 is a cell adhesion molecule that functions in tight junctions. Recent reports have implicated nectin-3 in pancreatic adenocarcinoma and lung adenocarcinoma. However, there has been little exploration of the expression, cellular invasion and migration of nectin-3 in ovarian cancer (OC). We evaluated the distribution of cells that were positive for nectin-3 using immunohistochemistry in specimens of human OC and correlated these results with...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
In this study, we further demonstrate the impact of ingredient contents of Citrus unshiu peel on the cancer's natural features.MethodsAnti-pancreatic cancer activities following combined treatment of naringenin and hesperetin were demonstrated in vitro and in vivo experiments.ResultsCombined treatment with naringenin and hesperetin inhibited the growth of human pancreatic cancer cells (εCUP mimic condition, P
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
ConclusionSQS III showed potent anti-cancer activity by inducing apoptosis and autophagy, which provides insights into its possible use as a therapy for melanoma.Graphical Abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
ConclusionTaken together, our results suggest that PAB exerts anti-cancer activity in HCC cells through inhibition of STAT3, ERK1/2, Akt, and GSK-3β/β-catenin carcinogenic signaling pathways, and may be used as a phytomedicine in the treatment of HCC.Graphical abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
We present here the first case of pazopanib-induced phototoxic drug reaction in a patient with renal cell carcinoma.Case Rep Dermatol 2018;10:251 –256
Source: Case Reports in Dermatology - Category: Dermatology Source Type: research
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