Larval Therapy for Chronic Cutaneous Ulcers Larval Therapy for Chronic Cutaneous Ulcers

Larval debridement has been historically used in the management of chronic ulcers, but does it still have a place in modern wound healing?Wounds
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

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International Wound Journal, EarlyView.
Source: International Wound Journal - Category: Surgery Authors: Source Type: research
An 8-year-old American Quarter Horse mare presented for acute, traumatic lacerations sustained along the ventral abdomen and hind limbs after an accident involving a manure spreader. A penetrating abdominal wound, extended through the peritoneum, was explored surgically. Peritoneal fluid drained from the abdominal wound for approximately 14 days, which was managed with absorbent bandages and a hernia belt. Wound debridement was augmented with medical maggot therapy initiated on day 11 of hospitalization.
Source: Journal of Equine Veterinary Science - Category: Veterinary Research Authors: Tags: Case Report Source Type: research
In this study, we quantified the courtship and mating behavior of L. sericata, shedding light on the impact of lateralization of selected behavioral traits during sexual interactions. When a male identified a female, he approached her with head pushing followed by foreleg tapping acts. Courtship lasted 7.65 ± 0.4 s. During copulation attempts, the male continued foreleg tapping acts on the female body, and tried to achieve genital contact. Copula lasted 14.88 ± 0.41 min, while male mating success was 85%. Several courtship and mating traits were found lateralized at p...
Source: Acta Tropica - Category: Infectious Diseases Authors: Tags: Acta Trop Source Type: research
The objective of this work was to bioprospect the salivary glands of Chrysomya megacephala (Fabricius, 1794) larvae, using ultrastructural, morphological, and histological observations, and the total protein electrophoretic profile. The salivary glands present a deferent duct, originating from the buccal cavity, which bifurcates into efferent ducts that insert through a slight dilatation to a pair of tubular-shaped tissues, united in the region of fat cells. Histologically, the secretion had protein characteristics. Cell cytoplasm presented numerous free ribosomes, autophagic vacuoles, spherical and elongated mitochondria,...
Source: Micron - Category: Biology Source Type: research
CONCLUSIONS: More research is needed to determine whether particular dressings or topical agents improve the probability of healing of venous leg ulcers. However, the NMA is uninformative regarding which interventions might best be included in a large trial, largely because of the low certainty of the whole network and of individual comparisons.The results of this NMA focus exclusively on complete healing; whilst this is of key importance to people living with venous leg ulcers, clinicians may wish to take into account other patient-important outcomes and factors such as patient preference and cost. PMID: 29906322 [Pu...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
Authors: Raposio E, Bortolini S, Maistrello L, Grasso DA Abstract Cutaneous ulcers tend to become chronic and have a profound impact on quality of life. These wounds may become infected and lead to greater morbidity and even mortality. In the past, larvae (ie, maggots) of certain common flies (Lucilia sericata and Lucilia cuprina) were considered useful in ulcer management because they only remove necrotic tissue while promoting healthy tissue in the wound bed, thus helping wounds heal faster. Recently, maggots from several other fly species (Calliphora vicina, Calliphora vomitoria, Phormia regina, Chrysomya albice...
Source: Wounds - Category: General Medicine Tags: Wounds Source Type: research
Publication date: Available online 13 October 2017 Source:Burns Author(s): Christoph Hirche, Antonella Citterio, Henk Hoeksema, Ján Koller, Martina Lehner, José Ramón Martinez, Stan Monstrey, Alexandra Murray, Jan A. Plock, Frank Sander, Alexandra Schulz, Benjamin Ziegler, Ulrich Kneser Early debridement and/or eschar removal is regarded as a significant step in the treatment of deep partial and full thickness burns. It aims to control wound bioburden and allows early wound closure by conservative treatment or skin grafting. Preservation of viable dermis accompanied by early wound closure, is regarded...
Source: Burns - Category: Dermatology Source Type: research
CONCLUSIONS: A network meta-analysis (NMA) of data from 39 studies (evaluating 21 dressings and topical agents for pressure ulcers) is sparse and the evidence is of low or very low certainty (due mainly to risk of bias and imprecision). Consequently we are unable to determine which dressings or topical agents are the most likely to heal pressure ulcers, and it is generally unclear whether the treatments examined are more effective than saline gauze.More research is needed to determine whether particular dressings or topical agents improve the probability of healing of pressure ulcers. The NMA is uninformative regarding whi...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
Journal of Wound Care,Volume 26, Issue 3, Page 137-143, March 2017.
Source: Journal of Wound Care - Category: Nursing Source Type: research
Abstract Maggots, through their excretions and secretions (ES), promote wound healing by removing necrotic tissue, counter bacterial infection, and activate wound associated cells. We investigated the effects of a physiological dose of maggot ES on four wound‐associated cell types in vitro with Affymetrix gene expression arrays; keratinocytes, endothelial cells, fibroblasts and monocytes. Keratinocytes showed the fewest (n=5; p
Source: Wound Repair and Regeneration - Category: Surgery Authors: Tags: Original Research ‐Basic Science Source Type: research
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