Larval Therapy for Chronic Cutaneous Ulcers Larval Therapy for Chronic Cutaneous Ulcers

Larval debridement has been historically used in the management of chronic ulcers, but does it still have a place in modern wound healing?Wounds
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

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Authors: Raposio E, Bortolini S, Maistrello L, Grasso DA Abstract Cutaneous ulcers tend to become chronic and have a profound impact on quality of life. These wounds may become infected and lead to greater morbidity and even mortality. In the past, larvae (ie, maggots) of certain common flies (Lucilia sericata and Lucilia cuprina) were considered useful in ulcer management because they only remove necrotic tissue while promoting healthy tissue in the wound bed, thus helping wounds heal faster. Recently, maggots from several other fly species (Calliphora vicina, Calliphora vomitoria, Phormia regina, Chrysomya albice...
Source: Wounds - Category: General Medicine Tags: Wounds Source Type: research
Publication date: Available online 13 October 2017 Source:Burns Author(s): Christoph Hirche, Antonella Citterio, Henk Hoeksema, Ján Koller, Martina Lehner, José Ramón Martinez, Stan Monstrey, Alexandra Murray, Jan A. Plock, Frank Sander, Alexandra Schulz, Benjamin Ziegler, Ulrich Kneser Early debridement and/or eschar removal is regarded as a significant step in the treatment of deep partial and full thickness burns. It aims to control wound bioburden and allows early wound closure by conservative treatment or skin grafting. Preservation of viable dermis accompanied by early wound closure, is regarded...
Source: Burns - Category: Dermatology Source Type: research
CONCLUSIONS: A network meta-analysis (NMA) of data from 39 studies (evaluating 21 dressings and topical agents for pressure ulcers) is sparse and the evidence is of low or very low certainty (due mainly to risk of bias and imprecision). Consequently we are unable to determine which dressings or topical agents are the most likely to heal pressure ulcers, and it is generally unclear whether the treatments examined are more effective than saline gauze.More research is needed to determine whether particular dressings or topical agents improve the probability of healing of pressure ulcers. The NMA is uninformative regarding whi...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
Journal of Wound Care,Volume 26, Issue 3, Page 137-143, March 2017.
Source: Journal of Wound Care - Category: Nursing Source Type: research
Abstract Maggots, through their excretions and secretions (ES), promote wound healing by removing necrotic tissue, counter bacterial infection, and activate wound associated cells. We investigated the effects of a physiological dose of maggot ES on four wound‐associated cell types in vitro with Affymetrix gene expression arrays; keratinocytes, endothelial cells, fibroblasts and monocytes. Keratinocytes showed the fewest (n=5; p
Source: Wound Repair and Regeneration - Category: Surgery Authors: Tags: Original Research ‐Basic Science Source Type: research
With the advent of online databases of medical literature, modern wound care specialists have at their disposal a vast body of knowledge to inform their clinical decision-making. From the massive quantity of published evidence, one can discern trends that have cemented a number of core tenets into the mind of every wound care practitioner: the importance of a moist wound healing environment to successful healing, the importance of dressing selection in effective exudate management throughout the course, of treatment and of course, the need to prepare the wound bed for optimal treatment and thus healing.
Source: Wounds UK - Category: Dermatology Source Type: research
This study's main objective was to evaluate the action of larval therapy derived from Lucilia sericata and Sarconesiopsis magellanica (blowflies) regarding Leishmania panamensis using an in vivo model. Eighteen golden hamsters (Mesocricetus auratus) were used; they were divided into 6 groups. The first three groups consisted of 4 animals each; these, in turn, were internally distributed into subgroups consisting of 2 hamsters to be used separately in treatments derived from each blowfly species. Group 1 was used in treating leishmanial lesions with larval therapy (LT), whilst the other two groups were used for evaluating t...
Source: Acta Tropica - Category: Infectious Diseases Authors: Tags: Acta Trop Source Type: research
Abstract After debridement and before dressing a wound with maggots of calliphorid flies, one frequently performed step is the application of antiseptics to the prepared wound bed. However, the concomitant application of antiseptic agents during maggot therapy is regarded controversial as antiseptics may interfere with maggots' viability. In this experimental in vitro study, the viability of fly maggots was investigated after exposure to various antiseptics frequently used in wound care. Here, we show that Lucilia sericata fly maggots can survive up to an hour's exposure to wound antiseptics such as octenidine, povidone‐...
Source: International Wound Journal - Category: Surgery Authors: Tags: ORIGINAL ARTICLE Source Type: research
RALEIGH, N.C. (CBS) – A new study about maggots might make your skin crawl, but it also has good news when it comes to treating wounds. “Maggot therapy” was approved by the FDA back in 2004 for cleaning wounds. Now, researchers at NC State University say that genetically modified green bottle fly larvae can actually help a wound heal faster. Scientists fed the modified maggots a special diet that caused them to secrete a human growth molecule that can accelerate wound healing. Maggot therapy can be especially useful for patients with diabetes, many of whom do not have access to more expensive forms of tre...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News Syndicated Local Source Type: news
Abstract The larvae of Lucillia sericata, or maggots of the green‐bottle fly, are used worldwide to help debride chronic, necrotic and infected wounds. Whilst there is abundant clinical and scientific evidence to support the role of maggots for debriding and disinfecting wounds, not so much emphasis has been placed on their role in stimulating wound healing. However, there is accumulating evidence to suggest that maggots and their externalized secretions may also promote wound healing in stubborn, recalcitrant chronic ulcers. There are a growing number of clinical reports which support the observation that wounds which h...
Source: Journal of the European Academy of Dermatology and Venereology - Category: Dermatology Authors: Tags: Review Article Source Type: research
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