Gene Assay Informs Chemo Decision in Breast Cancer (CME/CE)
(MedPage Today) -- 10-year recurrence risk of 3.5% in low-risk, node-positive disease
This article is protected by copyright. All rights reserved.
Authors: Suh DH, Kim M, Lee KH, Eom KY, Kjeldsen MK, Mirza MR, Kim JW Abstract In 2017, 10 topics were selected as major clinical research advances in gynecologic oncology. For cervical cancer, efficacy and safety analysis results of a 9-valent human papillomavirus (HPV) vaccine and long-term impact of reduced dose of quadrivalent vaccine were updated. Brief introduction of KEYNOTE trials of pembrolizumab, a monoclonal antibody that blocks the interaction between programmed death (PD)-1 and its ligands, PD-L1 and PD-L2, followed. Tailored surveillance programs for gynecologic cancer related with Lynch syndrome and ...
AbstractPurpose of reviewObesity contributes to an estimated forty-percent, or 630,000 cases, of malignant neoplasms diagnosed in the United States, and higher body mass index (BMI) has been associated with at least seventeen types of solid tumors, including 9% of all breast cancer cases. In this review, we discuss the impact of obesity and consequences of obesity, including the metabolic syndrome and type 2 diabetes mellitus, on breast cancer risk and recurrence.Recent findingsRecent work has identified multiple molecular mechanisms that may underlie the association between obesity and breast cancer. In particular, insuli...
The European committee recommended against approval of neratinib (Nerlynx) for breast cancer, even though the drug has been approved in the United States.International Approvals
Erin Silverman carried a baby for her sister, Randi Fishman, who was diagnosed with breast cancer at age 28.
According to this study. PMID: 29470222 [PubMed - in process]
Condition: Breast Cancer Triple Negative Intervention: Drug: Goserelin Sponsor: Kasr El Aini Hospital Not yet recruiting
Randi Fishman was diagnosed with breast cancer at age 28 and didn't think she would ever have kids.