Many breast cancer survivors may die of heart disease, doctors warn

(Reuters Health) - The same advances in breast cancer treatment that have dramatically improved survival in recent years have also left a growing number of women vulnerable to potentially fatal cardiovascular problems, the American Heart Association warns.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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Some chemotherapy treatments for breast cancer increase a woman's risk of heart...Read more on AuntMinnie.comRelated Reading: ASTRO: Imaging, radiation oncology increasingly work as one Breast cancer patients aren't getting heart disease treatment CE-MRI predicts survival in breast cancer patients after chemo JNM: Cancer patients need cardiac review Trastuzumab + RT = no cardiac risk in breast cancer
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
C, Corradini S Abstract PURPOSE: Aim of the current comparative modelling study was to estimate the individual radiation-induced risk for death of ischaemic heart disease (IHD) under free breathing (FB) and deep inspiration breath-hold (DIBH) in a real-world population. MATERIALS AND METHODS: Eighty-nine patients with left-sided early breast cancer were enrolled in the prospective SAVE-HEART study. For each patient three-dimensional conformal treatment plans were created in FB and DIBH and corresponding radiation-induced risks of IHD mortality were estimated based on expected survival, individual IHD risk fa...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Tags: Radiother Oncol Source Type: research
In the light of continuously improving long-term breast cancer (BC) survival rates [1], minimizing therapeutic morbidity has become a major topic of concern. The risk of heart disease mortality is significantly higher in women after radiotherapy as known from retrospective long-term follow-up data of randomized trials [2]. The results of a population-based case-control study of 2168 BC patients showed a linear correlation of the relative risk for major coronary events by 7.4% per Gray (Gy) increase in mean heart dose [3].
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Original article Source Type: research
Sustainable weight loss. Protection from diabetes, heart disease and cancer. Improved brain health. Enhanced physical fitness and strength. It seems like every week, researchers turn up some new and profound benefit associated with intermittent fasting: eating schedules that incorporate regular periods of low or no food consumption. By eating normally for several days a week and eating much less on the others, a person may be able to shift her body’s cellular and metabolic processes in ways that promote optimal health. And experts who study intermittent fasting say that while many blanks still need to be filled in, s...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Diet/Nutrition healthytime Source Type: news
Joint estimation of risks of radiation-induced secondary lung cancer (SLC) and ischemic heart disease (IHD) modeled with consideration of patient-level risk factors and risk of cancer recurrence caused by compromising target coverage.
Source: Physica Medica: European Journal of Medical Physics - Category: General Medicine Authors: Source Type: research
Publication date: May–June 2018Source: Practical Radiation Oncology, Volume 8, Issue 3Author(s): Julian C. Hong, Elham Rahimy, Cary P. Gross, Timothy Shafman, Xin Hu, James B. Yu, Rudi Ross, Steven E. Finkelstein, Arie Dosoretz, Henry S. Park, Pamela R. Soulos, Suzanne B. EvansAbstractPurposeAdjuvant radiation therapy (RT) for breast cancer improves outcomes, but prior studies have documented substantive cardiac dose and cardiac risk. We assessed the mean heart dose (MHD) of RT and estimated the risk of RT-associated cardiac toxicity in women undergoing adjuvant RT for breast cancer in contemporary (predominantly) co...
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
ConclusionAlthough routine implementation of DIBH requires significant resource commitments, it seems to be worthwhile regarding the projected reductions in cardiac mortality.
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
Publication date: May–June 2018Source: Practical Radiation Oncology, Volume 8, Issue 3Author(s): Julian C. Hong, Elham Rahimy, Cary P. Gross, Timothy Shafman, Xin Hu, James B. Yu, Rudi Ross, Steven E. Finkelstein, Arie Dosoretz, Henry S. Park, Pamela R. Soulos, Suzanne B. EvansAbstractPurposeAdjuvant radiation therapy (RT) for breast cancer improves outcomes, but prior studies have documented substantive cardiac dose and cardiac risk. We assessed the mean heart dose (MHD) of RT and estimated the risk of RT-associated cardiac toxicity in women undergoing adjuvant RT for breast cancer in contemporary (predominantly) co...
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
ConclusionAlthough routine implementation of DIBH requires significant resource commitments, it seems to be worthwhile regarding the projected reductions in cardiac mortality.
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
The objective of this work was to show how the influence of the microenvironment in tumor cells and consequently the onset and tumor progression is becoming increasingly more evident. Cancer is the second leading cause of death in the developed world, surpassed only by heart disease and obesity, and is increasingly recognised as an oncogenic factor in the genesis of this tumor. Inflammatory me- diators related to obesity are suspected to play a role in oncogenic modification of substrates metabolism of nutrients, most patients diagnosed with breast cancer underwent chemotherapy treatment, and this may be an aggravating fac...
Source: European Journal of Gynaecological Oncology - Category: OBGYN Tags: Eur J Gynaecol Oncol Source Type: research
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