Association between COMT Polymorphism Val158Met and Opioid Consumption in Patients with Postoperative Pain: A Meta-Analysis.

CONCLUSION: Patients with Val/Met but not Met/Met allele variant consumed less opioid, though larger and better-designed studies are required to obtain an exclusive conclusion about the correlation between postoperative pain and COMT Val158Met polymorphism. PMID: 29402857 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29402857?dopt=Abstract

Source: Neuro-Signals - January 25, 2018 Category: Neurology Authors: Hu B, Zhang X, Xu G, Zhang Q, Qian P, Liu S, Zhu J, Shen R Tags: Neurosignals Source Type: research