Cutting out asparagus may stop breast cancer spreading

Researchers from the Cancer Research UK Cambridge Institute found feeding mice with breast cancer a diet low in the the amino acid  asparagine reduces their tumours' ability to spread.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Publication date: Available online 14 February 2019Source: International Journal of PharmaceuticsAuthor(s): Gabriela Mojeiko, Moacir de Brito, Giovanna C. Salata, Luciana B. LopesAbstractIn spite of the high incidence of breast cancer worldwide, there are few strategies for its chemoprevention, and they have limited adherence mainly due to their serious adverse effects. As a new approach for local breast cancer chemoprevention, we developed and optimized microemulsions for topical delivery of celecoxib to the breast skin, and evaluated their combination with microneedles to improve drug penetration for localization in the ...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 14 February 2019Source: European Journal of Integrative MedicineAuthor(s): Ezgi Karadag EzgiAbstractIntroductionThe aim of this study was to examine the effect of a music listening intervention applied during radiation therapy on the anxiety and comfort level experienced by women with early-stage breast cancer.MethodThis randomized controlled study was conducted with 60 patients residing in a city located in the western Turkey. After providing informed consent, the Hospital Anxiety and Depression Scale (HADS), and Radiation Therapy Comfort Questionnaire (RTCQ) were administered. A music l...
Source: European Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
Tamoxifen, a medication commonly used to treat breast cancer, appears to hold some promise as a treatment for mania, according to asystematic review and meta-analysisappearing in theJournal of Psychopharmacology.Tamoxifen has been proposed as a treatment for bipolar disorder because it acts on cells in a way similar to lithium and valproate —both of which are effective medications for bipolar disorder. However, the current review found most studies focused on the effect of tamoxifen on mania, not on bipolar disorder, and its effects on depression are unknown.“Tamoxifen appears to be a promising potential treatm...
Source: Psychiatr News - Category: Psychiatry Tags: bipolar disorder depression Journal of Psychopharmacology literature search mania meta-analysis systematic review tamoxifen Source Type: research
The Internet of Things is driving incredible innovation in healthcare. “Almost any new innovative medical device is currently designed as a part of broader interconnected system,” Rami Muleys, head of application security business development at Positive Technologies, told MD+DI. “The main value of IoT is the convergence between different systems and the ability to exchange data between every device – from an insulin pump to a hospital bed.” Healthcare is consequently “a constantly changing landscape, especially sinc...
Source: MDDI - Category: Medical Devices Authors: Tags: Business Source Type: news
By analyzing tumor characteristics such as structure, shape, and size, an artificial...Read more on AuntMinnie.comRelated Reading: AI may predict lymph node metastasis in gastric cancer AI can predict breast cancer molecular subtypes on MRI Russian AI detects lung cancer on CT in 20 seconds AI can differentiate glioblastoma, brain metastasis AI uses features outside nodules to predict malignancy
Source: Headlines - Category: Radiology Source Type: news
Authors: Edge SB, Hortobagyi GN, Giuliano AE Abstract INTRODUCTION: Cancer staging has historically been based solely on the anatomic extent of the tumor (T), spread to lymph nodes (N), and presence of distant metastases (M). More recently biologic factors have been added to modify TNM stage groups to provide more accurate prognosis for patients. Areas covered: The American Joint Committee on Cancer (AJCC) updated breast cancer staging in 2016 to include T, N, M, tumor grade and expression of estrogen and progesterone receptors and HER2. Addition of these factors changed the stage group for a large fraction of case...
Source: Expert Review of Anticancer Therapy - Category: Cancer & Oncology Tags: Expert Rev Anticancer Ther Source Type: research
Publication date: Available online 15 February 2019Source: Journal of Molecular StructureAuthor(s): José A. Carmona-Negrón, Mariola M. Flores-Rivera, Alberto Santana, Arnold L. Rheingold, Enrique MeléndezAbstractThe ferrocene-hormone conjugate 16-ferrocenylidene-17β-estra-1,3,5-triene-3,17-diol crystallizes in a monoclinic unit cell, space group P21. The asymmetric unit cell contains two ferrocene-hormone conjugates, co-crystallized with two water and one acetonitrile molecules. The crystal structure shows a hydrogen bonding network within the hormone residues and the co-crystallized water and ace...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
This study aimed at investigating the relationship between the intakes of micronutrients involved in one-carbon metabolism with breast cancer (BrCa) and its subtype's odds. METHODS: Nutrients' intake from diet and supplements were collected through interviewing 151 cases and 154 controls by a 168-item semiquantitative food frequency questionnaire. Logistic regression was used to determine the relationship between dietary and/or total intake of studied nutrients and odds of BrCa and its subtypes. RESULTS: After adjusting the effects of confounding variables in the models, the odds of BrCa was significantly lower in ...
Source: International Journal for Vitamin and Nutrition Research - Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research
The top-selling drug is for the treatment of metastatic breast cancer.Medscape Medical News
Source: Medscape General Surgery Headlines - Category: Surgery Tags: Hematology-Oncology News Source Type: news
ConclusionsBPE could play a crucial role as an imaging bridge to molecular breast cancer subtype allowing an additional risk stratification in the field of breast MRI and targeted screening tests. Luminal B (HER2-) tumors could prevail in case of mild BPE on CE-MRI examinations and TN tumors in patients with marked BPE. Further studies on larger series are needed to confirm this hypothesis.
Source: European Journal of Radiology - Category: Radiology Source Type: research
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