Factors Influencing Graft Endothelial Cell Density after Descemet Stripping Automated Endothelial Keratoplasty.
Factors Influencing Graft Endothelial Cell Density after Descemet Stripping Automated Endothelial Keratoplasty. J Ophthalmic Vis Res. 2018 Jan-Mar;13(1):10-16 Authors: Javadi MA, Feizi S, Jafari R, Hosseini SB, Safapour S Abstract Purpose: To determine the factors that influence the endothelial cell density (ECD) of donor grafts after Descemet stripping automated endothelial keratoplasty (DSAEK). Methods: This retrospective, interventional case series comprised 77 eyes of 64 patients who underwent DSAEK. Confocal microscopy was performed at the final follow-up examination to evaluate the endothelial cell count, cell morphology, and graft thickness. Univariate and multiple linear regression analyses were used to investigate recipient-, donor-, surgical-, and postoperative related variables capable of influencing graft endothelial cell counts after DSAEK. Results: The mean patient age was 62.3 ± 15.6 years; patients were followed-up for 26.2 ± 20.9 months postoperatively. Forty-six eyes (59.7%) underwent stand-alone DSAEK; 31 eyes (40.3%) underwent DSAEK combined with cataract surgery. The donor trephination size was 8.0 ± 0.21 mm. The mean donor age was 30.4 ± 11.2 years, and the mean preoperative endothelial cell density was 3127.4 ± 315.1 cells/mm2, which decreased to 1788.6 ± 716.5 cells/mm2 postoperatively (P
Google (NSDQ:GOOG) life sciences company Verily said late last week that it is putting its joint project with Novartis (NYSE:NVS) unit Alcon to develop a glucose-sensing contact lens on hold due to difficulties in obtaining reliable tear glucose readings. The project, which began in 2014, aimed to develop a contact lens that could measure glucose levels for individuals living with diabetes, according to a blog post from Verily chief technical officer Brian Otis. But measuring glucose levels from tear glucose has proven to be unreliable, according to the blog posting. “Our clinical work on the gluc...
To investigate whether new dyes and dye combinations can give equivalent or better staining in anterior capsule surgery than existing dyes with a low degree of toxicity on relevant cells.
Two more smart contact lenses, for presbyopia and cataract surgery recovery, are still in the works.
To evaluate the long-term safety and efficacy of a trabecular microbypass stent as a sole procedure in pseudophakic eyes with open-angle glaucoma.
To evaluate the refractive and visual outcomes of arcuate incisions performed with the femtosecond laser in patients with a residual refractive astigmatism after refractive lens exchange (RLE) with trifocal intraocular lenses (IOLs).
Video recording is a unique solution to collect information about a surgery. Combined with computer vision and machine learning, it allows a wide range of applications, including automatic report generation, surgical skill evaluation and training, surgical workflow optimization, as well as warning and recommendation generation. Key indicators of what the surgeon is doing at any given time are the surgical tools that he or she is using. Therefore, several tool detection techniques have been presented in recent years (Bouget et al., 2017).
Conclusion: 360° anterior capsule polishing can effectively reduce the extent of the anterior capsule contraction and increase the stability of IOL. The study was registered at http://www.clinicaltrials.gov, and the clinical trial accession number is NCT 03142269. PMID: 30425856 [PubMed]
Conclusions: "Localized vitrectomy" has a high anatomical success rate in phakic eyes with primary uncomplicated macula-on RRD with intermediate retinal break(s) and marked vitreous traction, without causing progression of cataract. PMID: 30425854 [PubMed]
Conclusions: Sarcoid uveitis has similar characteristics in patients with new onset sarcoid uveitis after or without ophthalmic procedure. As a consequence, ophthalmic intervention should be seen as a potential trigger of latent sarcoidosis. PMID: 30420915 [PubMed]
CONCLUSIONS: Using an established genetic variant as a proxy for lifetime ascorbate concentrations, our results support a causal association of vitamin C with cataract. PMID: 30442817 [PubMed - as supplied by publisher]