Complement activation in hidradenitis suppurativa: a new pathway of pathogenesis?

CONCLUSIONS: Systemic complement activation occurs in HS and may be used as a surrogate biomarker of HS. C5a stimulates over-production of TNFα and may be a future therapeutic target. This article is protected by copyright. All rights reserved.
PMID: 29405257 [PubMed - as supplied by publisher]

Source: The British Journal of Dermatology - February 6, 2018 Category: Dermatology Authors: Kanni T, Zenker O, Habel M, Riedemann N, Giamarellos-Bourboulis EJ Tags: Br J Dermatol Source Type: research