Hyaluronan metabolism enhanced during epidermal differentiation is suppressed by vitamin C.

CONCLUSIONS: Epidermal stratification and maturation is associated with enhanced hyaluronan turnover, and release of large amounts of hyaluronan fragments. The high turnover is suppressed by vitamin C, which is suggested to enhance normal epidermal differentiation in part through its effect on hyaluronan. This article is protected by copyright. All rights reserved.
PMID: 29405260 [PubMed - as supplied by publisher]

Source: The British Journal of Dermatology - February 6, 2018 Category: Dermatology Authors: Hämäläinen L, Kärkkäinen E, Takabe P, Rauhala L, Bart G, Kärnä R, Pasonen-Seppänen S, Oikari S, Tammi MI, Tammi RH Tags: Br J Dermatol Source Type: research