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Bill Frist named to the board of Brentwood company

Former U.S. Sen. Bill Frist has been named to the board of directors for Brentwood-based MyNexus. First, founder of NashvilleHealth and co-founder of Aspire Health, has deep ties to Nashville’s health care industry as the son and brother of two of the founders of HCA Healthcare Inc. He is also a nationally acclaimed heart- and lung-transplant surgeon and an adjunct professor of cardiac surge ry at Vanderbilt University. “There are very few people in the world that have an understanding of the…
Source: bizjournals.com Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news

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Authors: Huang S, Tang Y, Zhu Z, Yang J, Zhang Z, Wang L, Sun C, Zhang Y, Zhao Q, Chen M, Wu L, Wang D, Ju W, Guo Z, He X Abstract BACKGROUND The inherent challenges of selecting an acceptable donor for the increasing number and acuity of recipients has forced programs to take increased risks, including accepting donors with a cancer history (DWCH). Outcomes of organ transplantation using organs from DWCH must be clarified. We assessed transplant outcomes of recipients of organs from DWCH. MATERIAL AND METHODS Retrospective analysis of the Scientific Registry of Transplant Recipients data from January 1, 2000 to De...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Renal rejection clinically represents a major cause of graft dysfunction and sadly the loss of the renal transplant. This is despite the considerable progress in immunosuppressive therapy. It is strongly believed that the complex immunologic network underlying the response against major histocompatibility molecules (MHC) is responsible for rejection, an unresolved issue that is, in part, not inhibited by the current prophylactic and therapeutic strategies. Extracorporeal photopheresis (ECP) is an effective cell therapy approach that was successfully used in immunomodulating heart rejection, acute and chronic GvHD, lung rej...
Source: Transfusion and Apheresis Science - Category: Hematology Authors: Tags: Review Source Type: research
Dear Editor,
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
We thank Dr. Bizouarn and colleagues for their interest in our publication1 and welcome their efforts in working towards meeting the public healthcare need for the treatment of advanced heart failure. The article Effects of pre-load variations on hemodynamic parameters with a pulsatile autoregulated artificial heart during the early post-operative period details the first clinical case using the Carmat Total Artificial Heart (C-TAH) with auto-mode functioning.2 Utilizing it in clinical practice was interesting, given that SynCardia Total Artificial Heart (TAH) also aims to operate under a similar mechanism with full eject parameters.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
Ex vivo lung perfusion (EVLP) has become one of the most promising techniques for allowing assessment and potential reconditioning of donor lungs being offered for lung transplantation. This technique was pioneered by Stig Steen in Lund1 and brought into more widespread clinical use by Marcelo Cypel and Shaf Keshavjee in Toronto.2,3 EVLP has the potential to revolutionize accessibility of lung transplantation, in a large part due to its ability to expand the pool of available donor lungs by at least 20%.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
In this prospective, single-center, observational study, we sought to investigate the association between repeated short periods of circulatory arrests with moderate hypothermia during pulmonary endarterectomy (PEA) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) and different neuropsychological dimensions.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Original Article Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Short-term outcomes of solid organ transplantation have improved dramatically over the past several decades; however, long-term survival has remained static over the same period, and chronic rejection remains a major cause of graft failure. The importance of donor, or “passenger,” lymphocytes to the induction of tolerance to allografts was recognized in the 1990s, but their precise contribution to graft acceptance or rejection has not been elucidated. Recently, specialized populations of tissue-resident lymphocytes in nonlymphoid organs have been described. These lymphocytes include tissue-resident memory T cel...
Source: Transplantation - Category: Transplant Surgery Tags: Reviews Source Type: research
Conclusions Induction with sc28AT promotes early cardiac allograft protection in hu5C8-treated NHPs. These results support further investigation of prolonged selective CD28 inhibition with CD40/CD154 blockade in NHP transplants.
Source: Transplantation - Category: Transplant Surgery Tags: Original Basic Science—General Source Type: research
Heart failure results in significant morbidity and mortality for young children with hypoplastic left heart syndrome (HLHS) following the Norwood procedure.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
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