The clinical usefulness of epicardial adipose tissue in patients with high-intermediate pre-test probability for coronary artery disease.

The clinical usefulness of epicardial adipose tissue in patients with high-intermediate pre-test probability for coronary artery disease. Kardiol Pol. 2018 Feb 05;: Authors: Zehir R, Güner A, Hayiroglu MI, Oz TK, Osken A, Aksu H, Dayi SU, Hobikoğlu GF Abstract BACKGROUND: Epicardial adipose tissue [EAT] is thought to be associated with extension and severity of coronary artery disease [CAD] and echocardiographic measurement of EAT thickness has been considered to be a possible cardiovascular risk indicator. ESC Task Force recommends further non-invasive testing in patients with an intermediate pre-test probability [PTP] for the diagnosis of CAD. AIM: The purpose of this study was to evaluate the clinical usefulness of performing EAT measurements in patients with a high-intermediate PTP. METHODS: Patients referred to an outpatient clinic with stable chest pain symptoms who had PTP between 66-85% for CAD were included in the study. Echocardiographic measurement of the EAT was identified as the echo-free space between the outer wall of the myocardium and the visceral layer of the pericardium. Single photon emission computed tomography [SPECT] was performed in all patients. The diagnosis of CAD was based on the presence of reversible perfusion defects on SPECT. RESULTS: A total of 126 patients [76 males, 60.3%] with a mean age of 65.3 [±9.1] years were recruited. The EAT thickness was 7.3 ± 0.7 mm in patients with positive ...
Source: Polish Heart Journal - Category: Cardiology Authors: Tags: Kardiol Pol Source Type: research

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AbstractEvaluation of atypical presentation of angina chest pain in emergency department is difficult. Hospitalization of this patient may impose additional costs and waste the time, early discharge may lead to miss the patients. The aim of this study was to determine volubility of Single Photon Emission Computed Tomography (SPECT) in management of patients admitted to emergency department with atypical manifestations of angina pain, un-diagnostic Electrocardiogram (ECG) and negative enzyme. Half of 100 patients admitted to emergency department with atypical chest pain and un-diagnostic ECG who were candidate for admission...
Source: The International Journal of Cardiovascular Imaging - Category: Radiology Source Type: research
GF Abstract BACKGROUND: Epicardial adipose tissue (EAT) is thought to be associated with the extension and severity of coronary artery disease (CAD), and echocardiographic measurement of EAT thickness is considered to be a possible cardiovascular risk indica-tor. The European Society of Cardiology Task Force recommends further non-invasive testing in patients with an intermediate pre-test probability (PTP) for the diagnosis of CAD. AIM: We sought to evaluate the clinical usefulness of performing EAT measurements in patients with a high-intermediate PTP. METHODS: Patients referred to an outpatient clinic...
Source: Kardiologia Polska - Category: Cardiology Authors: Tags: Kardiol Pol Source Type: research
Rationale: Ventilation/perfusion (V/Q) single-photon-emission computed tomography (SPECT) has arisen as an alternative to computed tomography pulmonary angiography (CTPA) in patients with pulmonary embolism (PE) suspicion. The addition of low dose CT (ldCT) to V/Q SPECT improves the specificity of the test, allowing for potential alternative diagnosis. Patient concerns and diagnosis: Here we presented a case of an aortic intramural hematoma (IMH) diagnosed on the ldCT portion of V/Q SPECT combined with CT. A 74-year-old man suffering from sudden-onset chest pain was referred to our nuclear medicine department for PE s...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
The aim of the present study was to evaluate the incidence of undiagnosed pulmonary arterial dilatation using the gated computed tomography (CT) images acquired in patients with an otherwise normal 99mTc-sestamibi single-photon-emission CT (SPECT)/CT myocardial perfusion study. This was a retrospective review of 200 consecutive patients (100 men, mean age 58.7 years) who underwent a myocardial perfusion 99mTc-sestamibi SPECT/CT study with normal perfusion and with gated CT images acquired for coronary calcium scoring. The CT images were reviewed using a previously validated mean main pulmonary artery diameter (mPAD) measu...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
This study was sought to assess whether acupuncture therapy at Neiguan (PC6) and Xinshu (BL15) in coronary heart disease (CHD) could increase the myocardial ischemia/perfusion and recover heart functions through single photon emission computed tomography ( SPECT) imaging. Furthermore, we compared the effects of acupuncture therapy with those of treating with nitroglycerine. Methods: 63 patients was diagnosed as CHD were randomly divided into two groups: one group received acupuncture (n=35 ) and the other group received nitroglycerine (n=28 cases). Firstly, the Myocardial Perfusion SPECT Imaging were performed during routi...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Cardiovascular Clinical Science Poster Session Source Type: research
If all three major coronary branches have similar degree of stenosis, the radionuclide used for perfusion study will have equal uptake in all regions of the myocardium. Thus a balanced three vessel coronary artery disease can produce a false negative myocardial perfusion scan. This situation is called balanced myocardial ischemia. In most cases this is picked up by the treadmill ECG usually done along with stress myocardial perfusion imaging. Since the ECG findings of myocardial ischemia does not depend on the relative perfusion in the coronary tree, ischemic changes will be noted in treadmill ECG even when nuclear ...
Source: Cardiophile MD - Category: Cardiology Authors: Tags: Nuclear Cardiology Source Type: blogs
CONCLUSIONS: We demonstrated therapy-related and stimulus-free longitudinal CBF changes in core areas of the pain matrix using ASL. ASL may act as a complementary noninvasive method to functional MRI and single-photon emission computed tomography / positron emission tomography, especially in the longitudinal assessment of pain response in clinical trials. PMID: 28770549 [PubMed - in process]
Source: Swiss Medical Weekly - Category: General Medicine Authors: Tags: Swiss Med Wkly Source Type: research
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Source: Journal of Nuclear Cardiology - Category: Nuclear Medicine Source Type: research
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Source: Annals of Nuclear Medicine - Category: Nuclear Medicine Source Type: research
Authors: Goldkorn R, Naimushin A, Beigel R, Naimushin E, Narodetski M, Matetzky S Abstract BACKGROUND: While patients presenting to emergency departments (ER) with chest pain are increasingly managed in chest pain units (CPU) that utilize accelerated diagnostic protocols for risk stratification, such as single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI), data are lacking regarding the prognostic implications of mildly abnormal scans in this population. OBJECTIVES: To evaluate the prognostic implications of mildly abnormal SPECT MPI results in patients with acute chest pain. ...
Source: The Israel Medical Association Journal - Category: General Medicine Tags: Isr Med Assoc J Source Type: research
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