Easing Your Child's Asthma

Title: Easing Your Child's AsthmaCategory: Health NewsCreated: 2/6/2018 12:00:00 AMLast Editorial Review: 2/6/2018 12:00:00 AM
Source: MedicineNet Asthma General - Category: Respiratory Medicine Source Type: news

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Protease-activated receptor 2 (PAR-2), an airway epithelial pattern recognition receptor (PRR), participates in the genesis of house dust mite–induced (HDM-induced) asthma. Here, we hypothesized that lung endothelial cells and proangiogenic hematopoietic progenitor cells (PACs) that express high levels of PAR-2 contribute to the initiation of atopic asthma. HDM extract (HDME) protease allergens were found deep in the airway mucosa and breaching the endothelial barrier. Lung endothelial cells and PACs released the Th2-promoting cytokines IL-1α and GM-CSF in response to HDME, and the endothelium had PAC-derived V...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Doctors on the island say they are seeing an alarming rise in the number and severity of asthma cases that they attribute to destruction caused by the deadly hurricane
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
Condition:   Asthma Interventions:   Drug: Dupilumab (SAR231893/REGN668);   Drug: Asthma controller therapies (incl. prednisone/prednisolone);   Drug: Asthma reliever therapies Sponsors:   Sanofi;   Regeneron Pharmaceuticals Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Progress in childhood asthma management has been made, but more work must be done to fully control this chronic condition.CDC Expert Commentary
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Pediatrics Commentary Source Type: news
(American College of Chest Physicians) To help enable stronger communication and understanding between the clinician and patient, the CHEST Foundation, the charitable foundation of the American College of Chest Physicians, Allergy&Asthma Network and American College of Allergy, Asthma&Immunology (ACAAI) have partnered to launch a new digital, interactive Shared Decision Making Tool.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
(American College of Chest Physicians) The American College of Chest Physicians (CHEST) announces a new partnership with Medscape focused on supporting physicians in addressing the challenges of diagnosing and treating moderate to severe asthma.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Discussion “Chiropractic is a health care profession concerned with the diagnosis, treatment, and prevention of disorders of the neuromusculoskeletal system and the effects of these disorders on general health.” Some people look at chiropractic care solely as spinal manipulative therapy (SMT) or manipulation. Chiropractic physicians also offer a variety of other treatments including nutritional advice, dietary or herbal supplements, therapeutic exercise, posture correction and behavioral counseling. Spinal muscle therapy or spinal manipulation is one of the most common complementary, integrative, and alternati...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
This study evaluates a novel bronchodilator, S1226, for its efficacy in reversing allergen-induced bronchoconstriction in subjects with mild, allergic asthma. S1226 is a new class of bronchodilator that is an aerosol/vapor/gas mixture combining pharmacological and biophysical principles for a novel mode of action. It contains a potent bronchodilator gas (carbon dioxide or CO2) and nebulized perflubron (a synthetic surfactant possessing mucolytic properties). It has demonstrated rapid reversal of allergen-induced bronchoconstriction in an ovine study model.MethodsThis was a phase IIa proof-of-concept, placebo-controlled, ra...
Source: Trials - Category: Research Source Type: clinical trials
AbstractObjectiveFraction of exhaled nitric oxide (FENO) has been proposed as a non-invasive biomarker for allergic inflammation seen in asthma. Many asthmatics in clinical practice have never had spirometry and recent data report misdiagnoses in patients with physician diagnosed (PD) asthma. The aim of this study was to assess the ability of FENO to discriminate between those with and without airflow obstruction (AO) among patients with PD-asthma.MethodsFrequent exacerbators of PD-asthma (with 2 or more asthma exacerbations leading to emergency room visit or hospitalization within last 12 months) were enrolled. All patien...
Source: Lung - Category: Respiratory Medicine Source Type: research
Authors: Rajendran V, Iqbal, Kumar V Abstract A case study of 35-year-old woman with persistent breathlessness and wheezing that had been unsuccessfully treated with inhaled beta 2-agonists and steroids for about two years. Patient developed dry cough and haemoptysis, so investigated further. Spirometry demonstrated a restrictive pattern. Chest CT demonstrated well defined hyperdense lesion in right middle lobe. Biopsy taken from the mass during bronchoscopy demonstrated the picture of atypical bronchial carcinoid. In this case, due to the lack of awareness, diagnosis of carcinoid was delayed by two years. PMID...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
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