The Growing Glaucoma Drug Landscape: Ophthalmology Times

(MedPage Today) -- Also, should we test new policies like we test new drugs?
Source: MedPage Today Primary Care - Category: Primary Care Source Type: news

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Conditions:   Glaucoma, Open-Angle;   Ocular Hypertension Intervention:   Drug: Netarsudil Ophthalmic Solution 0.02% Sponsor:   Aerie Pharmaceuticals Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Glaucoma Intervention:   Procedure: combined glaucoma surgery Sponsor:   Medical University of Bialystok Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Glaucoma, Open-Angle;   Ocular Hypertension Intervention:   Drug: Netarsudil Ophthalmic Solution 0.02% Sponsor:   Aerie Pharmaceuticals Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Glaucoma Intervention:   Procedure: combined glaucoma surgery Sponsor:   Medical University of Bialystok Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
OBJECTIVE: To determine where glaucoma patients most often fall and how integrated visual field (IVF) damage affects falls rates per year (falls/year) and per step (falls/step) at and away from home. DESIGN: Prospective, observational cohort study ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
AbstractPurposeComparison of the effect of mitomycin C (MMC) versus bevacizumab –methylcellulose mixture (BMM) on combined phacoemulsification and non-penetrating deep sclerectomy surgery on the intraocular pressure in patients with open-angle glaucoma was made.MethodsThe current study is a controlled, randomized, double-blind clinical trial. Thirty-eight patients were enrolled, with a total of 40 eyes, and underwent a combined phacoemulsification and non-penetrating deep sclerectomy surgery from 2016 to 2017. MMC with concentration of 0.2  mg/mL for 2 min was used for 20 eyes before separating the scl...
Source: International Ophthalmology - Category: Opthalmology Source Type: research
Condition:   Glaucoma, Open-Angle Interventions:   Diagnostic Test: Standard Automatic Perimetry Humphrey Field Analyzer;   Diagnostic Test: visuALL Field Analyzer Sponsors:   Wills Eye;   Olleyes, Inc. Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ABSTRACT Purpose: Obesity is associated with eye diseases, but the underlying structural changes and pathogenic mechanisms have not been examined in detail. Here, we assessed the effects of morbid obesity on the morphometric indices of eye disease. Methods: Morbidly obese volunteers (n=101, body mass index [BMI] ³40) and healthy individuals (n=95, BMI: 18.50-24.99) were examined by Goldman applanation tonometry, pachymetry, and spectral domain optical coherence tomography. Intraocular pressure, anterior chamber depth, axial length, central corneal thickness, retinal nerve fiber layer thickness, central fov eal thickne...
Source: Arquivos Brasileiros de Oftalmologia - Category: Opthalmology Source Type: research
CONCLUSIONS: Oxidative stress, inflammation and autophagy are implicated in biochemical and morphological changes in these ocular tissues. The development of therapy is a major target for the management care of these ocular diseases. PMID: 30644339 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - Category: Drugs & Pharmacology Authors: Tags: Curr Pharm Des Source Type: research
Abstract AIM:: To find out and compare various predictors of glaucoma-related visual impairments in primary and secondary glaucoma. METHODS:: A prospective observational study of patients, who were above 30 years of age. They were diagnosed as primary/secondary glaucoma with visual acuity
Source: European Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Eur J Ophthalmol Source Type: research
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