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Machine-learning model helps detect diabetic patients at risk for kidney damage

In this study, the company reported that the algorithm identified 45% of patients who experienced significant kidney damage within one year – 25% more patients than commonly-used clinical tools would have detected, according to Medial EarlySign. Get the full story at our sister site, Drug Delivery Business News. The post Machine-learning model helps detect diabetic patients at risk for kidney damage appeared first on MassDevice.
Source: Mass Device - Category: Medical Devices Authors: Tags: Diabetes Diagnostics Hospital Care mHealth (Mobile Health) Software / IT medialearlysign Source Type: news

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We describe a 68-year-old diabetic woman with disabling paroxysmal positioning upbeat nystagmus (UBN) exclusively in the supine position, associated with asymptomatic spontaneous DBN, alternating skew deviation and hyperactive vestibulo-ocular reflex responses on head impulse testing, in whom high titers of anti-GAD antibodies were detected. After treatment with intravenous immunoglobulin, a complete resolution of positioning UBN and spontaneous DBN occurred, along with a decrease in anti-GAD antibody titers. Positioning UBN in this case may reflect a transient disinhibition of the central vestibular pathways carrying post...
Source: Journal of Neuro-Ophthalmology - Category: Opthalmology Tags: Original Contribution Source Type: research
We describe a very rare case of concurrent variant type 3 autoimmune polyglandular syndrome (APS) and pulmonary arterial hypertension (PAH). A previously healthy 65-year-old Japanese woman was referred to our university hospital with a 2-month history of general fatigue and hyperglycemia. Laboratory tests revealed severe hyperglycemia (plasma glucose 543 mg/dL and HbA1c 10.7%) with ketonuria (3+). Glutamic acid decarboxylase (GAD) and IA-2 antibodies were positive, and the serum C peptide level was markedly decreased to 0.2 ng/mL. Accordingly, type 1 diabetes was diagnosed. Hashimoto's thyroiditis was also diagnosed becaus...
Source: Endocrine Journal - Category: Endocrinology Tags: Endocr J Source Type: research
In conclusion, SGLT2i reduced not only HbA1c, BW and BMI but also AHI significantly and therefore has potential as an effective treatment of OSAS. PMID: 29459554 [PubMed - as supplied by publisher]
Source: Endocrine Journal - Category: Endocrinology Tags: Endocr J Source Type: research
The more often people worked nights, the more likely they were to have Type 2 diabetes.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Diabetes Working Hours Source Type: news
CONCLUSIONS: This real-world study of non-neurogenic OAB patients treated with onabotulinumtoxinA suggests that the CIC rate is lower than the rates reported in previous studies. There were no significant correlations between baseline predictors and CIC initiation, although statistical significance may not have been reached because of the low incidence of CIC. PMID: 29458265 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
Express Scripts, one of the nation’s largest pharmacy benefit managers, reportedly plans to include Novo Nordisk‘s (NYSE:NVO) once-weekly Type II diabetes, Ozempic, on its 2018 formulary. The move puts Ozempic directly in competition with Eli Lilly‘s (NYSE:LLY) once-weekly Trulicity drug. Both products will also go up against AstraZeneca‘s (NYSE:AZN) once-weekly Bydureon medication. Get the full story at our sister site, Drug Delivery Business News. The post Express Scripts to include Novo Nordisk’s once-weekly diabetes drug on 2018 formulary appeared first on MassDevice.
Source: Mass Device - Category: Medical Devices Authors: Tags: Diabetes Drug-Device Combinations Pharmaceuticals Regulatory/Compliance Wall Street Beat Novo Nordisk Source Type: news
Conclusions: The present study identified novel changes in the coding transcriptome and non-coding RNAs in the livers of NAFLD mice after metformin treatment that might shed light on the underlying mechanism by which metformin impedes the progression of NAFLD.Cell Physiol Biochem 2018;45:1487 –1505
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research
Abstract The aim of this study is to produce the smart hydrogel to use insulin release for human body. p(HEMA-co-Eudragit L-100) hydrogels containing different ratios of 2-Hydroxyethyl methacrylate (HEMA) and Eudragait L-100 were synthesized by using ammonium persulfate (APS) as an initiator and ethylene glycol dimethacrylate (EGDMA) as a cross linker. The structures of hydrogels produced were characterized by using Fourier Transform Infrared Spectroscopy (FT-IR) and Scanning electron microscope (SEM) analysis. In this way, optimum synthesis conditions were determined for p(HEMA-co-Eudragit L-100) hydrogels by usi...
Source: Bio-Medical Materials and Engineering - Category: Materials Science Authors: Tags: Biomed Mater Eng Source Type: research
The following is a guest blog post by Brita Hansen, MD, Chief Medical Officer at LogicStream Health. In a value-based care environment, achieving quality and safety measures is a priority. Health systems must have the capabilities to measure a process following its initial implementation. The reality, however, is that traditional improvement methods are often plagued with lagging indicators that provide little (if any) insight into areas requiring corrective actions. Health systems have an opportunity to make a significant impact on patient care by focusing on three pillars of clinical process improvement and control: qual...
Source: EMR and HIPAA - Category: Information Technology Authors: Tags: Care Management System Health Care Healthcare Analytics Healthcare CIO HealthCare IT Brita Hansen LogicStream Health Source Type: blogs
Authors: Lingam S, Rani P, Sheeladevi S, Kotapati V, Das T Abstract INTRODUCTION: To report the results of a knowledge, attitude and practice (KAP) study related to diabetes mellitus (DM), hypertension and diabetic retinopathy (DR) of patient populations in India at different levels (Tertiary (T), Secondary (S) and Primary (P)) of a pyramidal model of eye health care. METHODS: In total, 202 participants, composed of equal numbers of diabetic and non-diabetic patients at a Tertiary urban facility (T), a Secondary rural facility (S) and a Primary (P) community-screening program, were surveyed on their knowledge, ...
Source: Rural and Remote Health - Category: Rural Health Tags: Rural Remote Health Source Type: research
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