Toll-like receptor 4 polymorphisms and bacterial infections in patients with cirrhosis and ascites.
CONCLUSION: Genetic polymorphisms D299G and/or T399I of TLR4 do not seem to play a relevant role in the predisposition of cirrhotic patients with ascites to bacterial infections. PMID: 29399286 [PubMed]
Publication date: May 2020Source: Journal of Comparative Pathology, Volume 177Author(s): L.M.C. Soares, A.H.B. Pereira, C.G. de Campos, L.S. Rocha, T.Á. dos Santos, M.A. Souza, P.C. Jark, C.A. Pescador
Psychologists say anxiety and uncertainty prompt irrational decisions — like turning down a transplant when an organ becomes available.
This study, for instance, attributes a patient’s waitlist/transplant outcome to the very last dialysis facility the patient was associated with. In epidemiology speak, this means the causal inference authors are trying to draw between for-profit status and good transplant outcomes is subject to time-varying confounding. As an example, if one is seeking an association between testosterone levels and risk of a heart attack, using the last testosterone level available would be a poor way of doing this study because testosterone levels are known to vary over time. The same applies to dialysis facilities. Patie...
Publication date: 5 August 2020Source: Journal of Pharmaceutical and Biomedical Analysis, Volume 187Author(s): Valentina Iacuzzi, Martina Zanchetta, Sara Gagno, Ariana Soledad Poetto, Marco Orleni, Elena Marangon, Michela Guardascione, Luisa Foltran, Bianca Posocco, Giuseppe Toffoli
CONCLUSIONS: The findings indicate that the Polish adaptation of the SBQ-R by Osman et al. has good psychometric characteristics and can be considered in both research and clinical practice. PMID: 32447359 [PubMed - as supplied by publisher]
A new Yale study has found 19 previously unknown genetic risk factors for problematic alcohol use, and confirmed 10 previously identified risk factors.
HOW TO live longer: The secret to long life expectancy is a healthy lifestyle, which includes eating a healthy, balanced diet, not smoking, limiting alcohol intake, getting plenty of sleep and regular exercise. But when it comes to exercise, which one is best?
In South Africa, little is known about alcohol consumption patterns, such as drinks consumed, container size, salience of alcohol price, affordability and availability, and perceptions of alcohol policies as potential predictors of heavy episodic alcohol (...
INTRODUCTION: Young adults reporting combined alcohol and marijuana use indicate greater frequency of other substances, binge drinking rates, and alcohol-related negative consequences. Emotion regulation (ER) difficulties are linked to alcohol use and abus...