GPs advised on flu vaccines for 2018/19 as NHS promises extra funds

GPs, pharmacists and CCGs have been reminded of official advice on the most effective vaccines for patients in at-risk groups and over-65s, as NHS England pledged extra funding for the 2018/19 flu season.
Source: GP Online News - Category: Primary Care Tags: Influenza Source Type: news

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The TWiVerati follow up on the Ebola virus outbreak, virulence of Ebola-Makona, and reveal how a parasitoid is revealed to hyperparasitoids, and binding of influenza virus to a calcium ion channel to mediate influenza virus entry. Hosts: Vincent Racaniello, Alan Dove, and Kathy Spindler Become a patron of TWiV! Links for this episode ASM Microbe 2018 Support Viruses &Cells Gordon Conference Faculty positions at Icahn School of Medicine International dsRNA Virus Symposium Tracing Ebola virus contacts(CIDRAP) WHO FAQ Ebola virus vaccine(WHO) Nipah virusoutbreak (CIDRAP) Revealingparasitoid t...
Source: This Week in Virology - MP3 Edition - Category: Virology Authors: Source Type: podcasts
We reported a 28-year-old healthy woman presented with subacute onset ascending muscle weakness 2 weeks after an annual influenza vaccination. Cerebral Spinal Fluid study showed normal cell counts with elevated protein and nerve conduction study showed reduced diffuse compound muscle action potential amplitudes suggesting a diagnosis of Guillain–Barré syndrome. Despite treatment using intravenous immunoglobulin, her condition continued to get worse with new bulbar and respiratory muscle weakness. Eventually, the diagnosis of anti–single recognition particle–mediated necrotizing myopathy was made ba...
Source: Journal of Clinical Neuromuscular Disease - Category: Neurology Tags: Case Review Source Type: research
Publication date: July 2018 Source:Microbial Pathogenesis, Volume 120 Author(s): Cong Zhang, Jiangfei Zhou, Kairui Cai, Wufan Zhang, Chengshui Liao, Chen Wang Thymosin α1 (Tα1) and bursin-like peptide (BLP) are both immunopotentiators. In order to investigate adjuvant of thymosin α1-bursin-like peptide (Tα1-BLP), we cloned the gene of Tα1-BLP and provided evidence that the gene of Tα1-BLP in a recombinant prokaryotic expression plasmid was successfully expressed in E. coli BL21. To evaluate the immune adjuvant properties of Tα1-BLP, chickens were immunized with Tα1-BLP combi...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Influenza and Other Respiratory Viruses, EarlyView.
Source: Influenza and Other Respiratory Viruses - Category: Virology Authors: Source Type: research
For the upcoming 2018-2019 flu season, the AAP recommends sticking with the inactivated influenza vaccine, which provides better protection; the nasal spray should only be used in kids who refuse shots.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Pediatrics News Source Type: news
Conclusion INVESTED is the largest and longest study to assess whether high-dose influenza vaccine is superior to standard-dose influenza vaccine in reducing cardiopulmonary events in a high-risk cardiovascular population patients with heart failure and/or myocardial infarction (ClinicalTrials.gov Identifier: NCT02787044).
Source: American Heart Journal - Category: Cardiology Source Type: research
In this study, protective media containing no animal proteins and lyophilization regimen were determined. The optimum lyophilization regimen consisted of three stages: freezing at -70 °C, main stage at -35°C, and drying at 24°C. Protective medium containing 4% trehalose or protective medium with 10% sucrose and 5% soy peptone ensured highest stability of the lyophilized vaccine preparation in temperature range of 4-24°C. This can help to overcome possible break in the cold ch ain, which is important during transporting or storage of vaccine preparations.
Source: Bulletin of Experimental Biology and Medicine - Category: Biology Source Type: research
aki Nanogels are drug delivery systems that can bypass the blood-brain barrier and deliver drugs to the desired site when administered intranasally. They have been used as a drug delivery platform for the management of brain diseases such as Alzheimer disease, migraine, schizophrenia and depression. nanogels have also been developed as vaccine carriers for the protection of bacterial infections such as influenza, meningitis, pneumonia and as veterinary vaccine carriers for the protection of animals from encephalomyelitis and mouth to foot disease. It has been developed as vaccine carriers for the prevention of lifestyl...
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research
S. M. Mahmud et al.
Source: Emerging Infectious Diseases Journal - Category: Infectious Diseases Source Type: research
ConclusionsAlthough this is a non-randomized trial with a limited number of patients, the increased rate of immunological toxicity is concerning. This finding should be studied in a larger patient population.
Source: Journal for Immunotherapy of Cancer - Category: Cancer & Oncology Source Type: research
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