Randomized controlled trial of honey versus mupirocin to decolonize patients with nasal colonization of meticillin-resistant Staphylococcus aureus

Conclusion Although not significant, a decolonization rate of 42.8% for MGH was impressive. Our findings suggest that this strategy, which has the potential to combat antimicrobial resistance, should be assessed in similar but larger studies.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research

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ConclusionsThe results indicated a high prevalence ofS. arueus and MRSA nasal colonization among pediatric ICU patients in Taiwan. Identification of epidemic clones warrants the implement of infection control measures to reduce colonization and prevent the dissemination of MRSA in hospitals.
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research
Authors: Blakiston MR, Freeman JT Abstract AIMS: National responses to antimicrobial resistance (AMR) require an understanding of the factors driving its development and spread. Research to date has primarily focused on determining individual-level risk factors for AMR-associated infections. However, additional insights may be gained by investigating exposures associated with AMR variation at the population level. METHODS: We used an ecological study design to describe the association between the incidence rate of methicillin-resistant Staphylococcus aureus (MRSA) and extended-spectrum β-lactamase producin...
Source: New Zealand Medical Journal - Category: General Medicine Tags: N Z Med J Source Type: research
Publication date: Available online 14 February 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): Sinan Mermer, Tuncer Turhan, Elif Bolat, Sohret Aydemir, Tansu Yamazhan, Husnu Pullukcu, Bilgin Arda, Hilal Sipahi, Sercan Ulusoy, Oguz Resat SipahiAbstractObjectivesHerein, we aimed to compare the antibacterial activity of ceftaroline and vancomycin in the treatment of MRSA meningitis in experimental rabbit meningitis model.MethodsWe compared the antibacterial activity of ceftaroline with vancomycin in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) meningitis (induced by MRSA strain ATCC 433...
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
ConclusionsThese findings highlight the need to evaluate phenotypic methods using mecA-positive S. lugdunensis with different oxacillin resistance phenotypes.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
In conclusion, wastewater effluents from the investigated poultry slaughterhouses exhibited clinically relevant bacteria (E. coli, MRSA, K. pneumoniae, species of the ACB-and E. cloacae-complexes) that contribute to the dissemination of clinically relevant resistances (i.e. bla CTX-M/SHV, mcr-1) in the environment.Importance Bacteria from livestock may be opportunistic pathogens and carriers of clinically relevant resistance genes, as many antimicrobials are used both in veterinary and human medicine. They may be released into the environment from wastewater treatment plants (WWTPs) that are influenced by wastewater from s...
Source: Applied and Environmental Microbiology - Category: Microbiology Authors: Tags: Appl Environ Microbiol Source Type: research
The spread of drug-resistant bacteria is considered a global public health problem. According to the World Health Organization (World Health Organization [Internet], 2014), it is anticipated that around 10 million people could die from infections with drug-resistant bacteria by 2050. In Japan, in addition to drug-resistant Gram-positive cocci such as methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci, healthcare-associated infections caused by drug-resistant Gram-negative bacilli, including multidrug-resistant Pseudomonas aeruginosa (MDRP) and multidrug-resistant Acinetobacter still rem...
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
ConclusionsThese data give new insight into the epidemiology of veterinary methicillin-resistant staphylococci to inform future surveillance and zoonotic risk evaluation. Our data indicate that MRSA has likely decreased in prevalence since earlier survey work in England and Wales during 2011-12 and highlights the diversity of methicillin resistance and other resistance determinants among bovine-associated staphylococci with implications for veterinary and human medicine.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
ConclusionsOur current results demonstrated that LysSS can be a novel and promising antimicrobial agent against MRSA and MDR Gram-negative bacteria includingA. baumannii and P. aeruginosa.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
Conclusion: Our findings raise potential public health concerns for environmental contamination of MRSA and MRSE in school environments. Surfaces of school environments may potentially provide a source for cross-contamination with these bacteria into the wider community.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
This study provides insights into the virulence, pathogenicity, and antimicrobial resistance determinants of methicillin ‐susceptible and methicillin‐resistantS. aureus (MSSA; MRSA) recovered from non ‐healthcare environments. Three environmental MSSA and three environmental MRSA are selected for proteomic profiling using isobaric tag for relative and absolute quantitation tandem mass spectrometry (iTRAQ MS/MS). Gene Ontology annotation and Kyoto Encyclopedia of Genes and Genomes pathway annota tion are applied to interpret the functions of the proteins detected. 792 proteins are identified in MSSA and MRSA. Comparat...
Source: Proteomics - Category: Biochemistry Authors: Tags: Dataset Brief Source Type: research
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