Diet switch and omega-3 hydroxy-fatty acids display differential hepatoprotective effects in an obesity/nonalcoholic fatty liver disease model in mice.
CONCLUSION: 18-HEPE and 17-HDHA differentially exert hepatoprotective effects through up-regulation of nuclear receptors PPARα/γ and amelioration of serum adipokines profile.
PMID: 29398867 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Rodriguez-Echevarria R, Macias-Barragan J, Parra-Vargas M, Davila-Rodriguez JR, Amezcua-Galvez E, Armendariz-Borunda J Tags: World J Gastroenterol Source Type: research