Overexpression of CREPT confers colorectal cancer sensitivity to fluorouracil.

CONCLUSION: Aberrant overexpression of CREPT contributes to tumorigenesis of CRC by promoting cell proliferation and accelerating the cell cycle, and confers sensitivity to 5-FU. CREPT is a potential prognostic biomarker for 5-FU in CRC.
PMID: 29398868 [PubMed - in process]

Source: World Journal of Gastroenterology : WJG - January 28, 2018 Category: Gastroenterology Authors: Kuang YS, Wang Y, Ding LD, Yang L, Wang Y, Liu SH, Zhu BT, Wang XN, Liu HY, Li J, Chang ZJ, Wang YY, Jia BQ Tags: World J Gastroenterol Source Type: research