Intraductal papillary bile duct adenocarcinoma and gastrointestinal stromal tumor in a case of neurofibromatosis type 1.
We report our experience with a synchronous case of gastrointestinal stromal tumor (GIST) and intraductal papillary neoplasm of the bile duct (IPNB) in an elderly woman with neurofibromatosis type 1 (NF-1). A 72-year-old woman presented with a 2-mo history of right upper abdominal pain unrelated to diet and indigestion. Fourteen years earlier, she had been diagnosed with NF-1, which manifested as café au lait spots and multiple nodules on the skin. Computed tomography (CT) revealed a multilocular low-density mass with septation, and mural nodules in the right hepatic lobe, as well as a 1.7-cm-sized well-demarcated enhancing mass in the third portion of the duodenum. The patient subsequently underwent right hepatectomy and duodenal wedge resection. We present here the first report of a case involving a synchronous IPNB and GIST in a patient with NF-1. Our findings demonstrate the possibility of various tumors in NF-1 patients and the importance of diagnosis at an early stage. PMID: 29398874 [PubMed - in process]
Authors: Gentile E, Ricci K, Delussi M, Brighina F, de Tommaso M Abstract Previous studies indicated changes of motor cortex excitability in fibromyalgia (FM) patients and the positive results of transcranial stimulation techniques. The present study aimed to explore the metabolism of motor cortex in FM patients, in resting state and during slow and fast finger tapping, using functional Near-Infrared Spectroscopy (fNIRS), an optical method which detects in real time the metabolism changes in the cortical tissue. We studied 24 FM patients and 24 healthy subjects. We found a significant slowness of motor speed in FM ...
The indications for cryoablation in pediatric patients has been slowly growing over the last few years. Vascular anomalies and solid tumors are being treated with this modality. However, cryoablation can be associated with local complications. This is of high relevance in children due to smaller body surface area, more compact anatomy and less subcutaneous fat. Additionally, these patients have lower tolerance to pain and inflammation. It is critical to understand these factors when using cryoablation to treat pediatric patients.
To evaluate the ability of pre-procedural CTA to predict the technical success of embolization of post-EVAR type II endoleaks arising from lumbar arteries.
Knee OA is a common cause of pain and disability, with many patients relying on chronic pain medications and/or joint injections. These options unfortunately result in short-term relief, or have associated increased morbidity, and knee replacement surgery may ultimately be performed. Researchers have postulated that synovial neovascularity develops as a result of inflammation and subsequently leads to knee pain. While previous overseas reports of success with GAE have been published, we present our final results from a prospective US multicenter clinical trial.
There are no reported descriptions of motor nerve cryoablation in humans. As a result, physicians faced with inadvertent motor nerve cryoablation during palliative or therapeutic procedures for established indications are forced to rely on preclinical studies to manage patient expectations. (1, 2) In addition, potential applications of motor nerve cryoablation, such as for management of spasticity and pain, have been avoided because of the unknown prognosis following cryoneurolysis of mixed or motor nerves.
Ultrasound image-guided procedures (USGP) are common and often cause mild to moderate pain both during the procedure and during lidocaine injection. This 110 participant randomized clinical trial evaluated the effectiveness of vapocoolant topical anesthetic application prior to lidocaine injection at reducing pain during the USGP.
To develop a model to estimate drug dose delivered to the liver following transarterial chemoembolization (TACE) with radiopaque drug-eluting beads (RO DEB) based on bead density and cone-beam computed tomography (CBCT) in a woodchuck hepatoma model.
Computed tomography (CT) interventions are often performed using a helical acquisition technique while the operator is in a control room. We compare an axial technique using a gantry-side pedal to the helical technique for chest biopsies in terms of time, number of acquisitions, and radiation dose to operator and patient.
This study aims to evaluate the utility of second look imaging in patients with persistent clinical concern for LGIB after initial negative CTA.
Many institutions advocate for obtaining arterial (Art), non-contrast (NC), and delayed (Del) phases when assessing for active lower gastrointestinal bleed (LGIB) on multiphasic computed tomography arteriograms (CTA). We aimed to evaluate the necessity of all three phases of CTA for accurate diagnosis of active LGIB.