Regional Variation in Technetium Pyrophosphate Uptake in Transthyretin Cardiac Amyloidosis and Impact on Mortality

Conclusions There is decreased TcPYP uptake in apical as compared to mid and basal segments in the LV, mimicking apical-sparing LS seen on echocardiography. Regional distribution of LV TcPYP uptake is associated with mortality, whereas overall amount of uptake as measured by H/CL ratio and indexed LV SPECT uptake is not.

http://www.imaging.onlinejacc.org/cgi/content/short/11/2_Part_1/234?rss=1

Source: Journal of the American College of Cardiology: Cardiovascular Imaging - February 5, 2018 Category: Radiology Authors: Sperry, B. W., Vranian, M. N., Tower-Rader, A., Hachamovitch, R., Hanna, M., Brunken, R., Phelan, D., Cerqueira, M. D., Jaber, W. A. Tags: Original Research Source Type: research