Reply to: “The role of NAFLD in extrahepatic malignancies: The importance of ruling out the effect of obesity”

We thank Bo Zheng et al. for their interest in our study and for providing a valuable comment.1 Our study investigated the little understood relationship between non-alcoholic fatty liver disease (NAFLD) and extrahepatic cancers,2 and found that NAFLD was highly associated with the development of hepatocellular carcinoma (HCC), colorectal cancer in males, and breast cancer in females. This association suggests that NAFLD can serve as a risk factor of extrahepatic malignancies.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Letter to the Editor Source Type: research

Related Links:

Publication date: January 2019Source: Journal of Molecular Liquids, Volume 273Author(s): Mohammed Taghi Zafarani-Moattar, Hemayat Shekaari, Parisa JafariAbstract1-propanol or 2-propanol and water form azeotropic mixtures with the minimum boiling point at constant pressure. The separation of these azeotropes is an important issue in the chemical industries. Their separation by simple distillation is basically impossible, and the extractive distillation consumes much more energy than liquid- liquid extraction. For a better understanding of extraction processes, liquid-liquid equilibrium data containing binodal data and tie-l...
Source: Journal of Molecular Liquids - Category: Molecular Biology Source Type: research
Publication date: Available online 18 October 2018Source: Journal of Molecular LiquidsAuthor(s): Dáfenes B.R. dos S. Silva, Lindembergue P.C. Júnior, Maurício F. de Aguiar, Celso P. de Melo, Kleber G.B. AlvesAbstractThis work describes the preparation of polyvinyl alcohol/polyaniline-montmorillonite clay (PVA/PANI-OMMT) nanofibers through electrospinning. Initially, for improving the compatibility of the clay towards the organic polymer, the montmorillonite (MMT) was submitted to an organophilization process using hexadecyltrimethylammonium bromide (CH3(CH2)15N(Br)(CH3)3). The PANI-OMMT composite, whic...
Source: Journal of Molecular Liquids - Category: Molecular Biology Source Type: research
Publication date: Available online 18 October 2018Source: Journal of Molecular LiquidsAuthor(s): H. Abramczyk, A. Imiela, A. ŚliwińskaAbstractLipids play an important role in many cellular processes. Raman-driven microscopy is one of the most powerful technique for analyzing the properties of lipids in cellular compartments offering lipid compositional mapping and more precise, faster, simpler, and nondestructive measurements. Recent advances in Raman imaging (RI) have greatly progressed lipidomic analysis, such as lipid droplet content, lipid phenotype, fatty acid composition, spatial distribution and drug treatment res...
Source: Journal of Molecular Liquids - Category: Molecular Biology Source Type: research
Publication date: Available online 18 October 2018Source: Journal of Molecular LiquidsAuthor(s): Mostafa Zamani, Ehsan Naderi, Mozhgan Aghajanzadeh, Mahmoud Naseri, Ali Sharafi, Hossein DanafarAbstractThe present paper aimed to synthesize, using thermal-treatment method, a variety of Co1-XZnxFe2O4-based nanocarriers (NCs) as Dual-controlled and targeted drug delivery systems (DDS) and provide a new structure as NCs suitable for the loading and pH-responsive characteristics of the chemotherapeutic curcumin (CUR). To study the structure, surface morphology, surface charge and magnetic properties of NCs, X-ray diffraction (XR...
Source: Journal of Molecular Liquids - Category: Molecular Biology Source Type: research
This study examined the role of H2S in drug resistance in liver cancer cells.Materials and methodsHuman primary hepatocellular carcinoma cell line (HepG2) and doxorubicin (Dox)-resistant cells were used in this study. Cell survival was analyzed by MTT, Annexin V-FITC/propidium iodide staining and clonogenic assay. Western blotting was used for analysis of protein expression, and immunoprecipitation was used to determine interactions of LXR/RXR.Key findingsThe expression of H2S-generating enzyme cystathionine gamma-lyase (CSE) was inhibited by doxorubicin treatment in HepG2 cells, and H2S sensitized Dox-inhibited cell survi...
Source: Life Sciences - Category: Biology Source Type: research
This study was based on the fact that, overall mass, charge and size of a protein changes after interaction with charged ligands such as metal ions, which affects the electrophoretic movement of the analyte protein under the influence of electroosmotic flow. This alteration in electrophoretic mobility of the analyte is proportional to the strength of interaction between the two species and is utilized to calculate the binding results. The mobility ratio (R) of an EOF marker (injected in same run) and the analyte enzyme was determined and the binding result was expressed as the normalized difference of the mobility ratios o...
Source: Microchemical Journal - Category: Chemistry Source Type: research
Publication date: Available online 18 October 2018Source: Genes &DiseasesAuthor(s): Xingxing Zang
Source: Genes and Diseases - Category: Genetics & Stem Cells Source Type: research
We appreciate Bo Zheng et al. for their interest in our study and for providing a valuable comment. Our study investigated the little understood relationship between non-alcoholic fatty liver disease (NAFLD) and extrahepatic cancers [1], and found that NAFLD was highly associated with the development of hepatocellular carcinoma (HCC), colorectal cancer in males, and breast cancer in females. This association suggests that NAFLD can serve as a risk factor of extrahepatic malignancies.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Letter to the Editor Source Type: research
We read with great interests the article by Gi-Ae et al[1]. Non-alcoholic fatty liver disease(NAFLD) is strongly associated with metabolic disorders such as insulin resistance, diabetes and cardiovascular diseases which implies that NAFLD might have an important part in extrahepatic complications. Gi-Ae et al not only confirmed that NAFLD is closely related to the development of hepatocellular carcinoma but also demonstrated that NAFLD is a risk factor for extrahepatic malignancies such as male colorectal carcinoma and female breast cancer.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Source Type: research
We thank Bo Zheng et al. for their interest in our study and for providing a valuable comment.1 Our study investigated the little understood relationship between non-alcoholic fatty liver disease (NAFLD) and extrahepatic cancers,2 and found that NAFLD was highly associated with the development of hepatocellular carcinoma (HCC), colorectal cancer in males, and breast cancer in females. This association suggests that NAFLD can serve as a risk factor of extrahepatic malignancies.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Letter to the Editor Source Type: research
More News: Alcoholism | Breast Cancer | Breast Carcinoma | Cancer | Cancer & Oncology | Carcinoma | Colorectal Cancer | Fatty Liver Disease (FLD) | Gastroenterology | Hepatocellular Carcinoma | Liver | Liver Cancer | Liver Disease | Non-alcoholic Fatty Liver Diseases (NAFLD) | Study | Urology & Nephrology