Refining risk in diabetes and CAD with SPECT MPI: New insights and future challenges
CONCLUSION: We suppose that sleep modify the glucose counterregulatory responses with increased growth hormone, which salvage hypoglycemic status in our presented case. With this report, we would like to draw clinicians' attention to including the treatable hypoglycemia state in the differential diagnosis of episodic involuntary movements. PMID: 30315558 [PubMed - in process]
ConclusionTen percent of patients with T2DM with no clinical evidence of CAD were found to have evidence of asymptomatic ischemia or infarction.
AbstractObjectiveTo test whether phase analysis indices from SPECT-MPI for left ventricular mechanical dyssynchrony (LVMD) are predictors of major adverse cardiac events (MACEs) in long-standing diabetes mellitus (DM).MethodsA total of 136 DM patients with normal perfusion and left ventricular systolic functions were followed up for about two years and divided into two groups according to the presence and the absence of MACEs.ResultThirteen (9.5%) patients experienced MACEs during follow-up. Patients experiencing MACEs showed significantly higher phase standard deviation (PSD) and wider phase bandwidth (PBW) than those who...
This article reviews the most frequent clinical challenges in patients after foot and ankle surgery, including a description of the various surgical procedures, the different imaging options with their advantages and disadvantages, and aims to integrate bone SPECT/CT into the clinical diagnostic workup. PMID: 30193651 [PubMed - in process]
CONCLUSION: Factors other than hypoperfusion, such as hypertension and diabetes mellitus, could be involved in the cognitive dysfunction of late-onset AD patients with high vascular risk. PMID: 30132427 [PubMed - as supplied by publisher]
ConclusionsMyocardial glucose utilization was influenced by substrates and medications, including statins and DPP4i. MRGlu could discriminate between viable and non-viable myocardium, and MRGlu in transmural match and reverse mismatch may be prognostic predictors of cardiovascular death in patients with ischemic cardiomyopathy.
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ConclusionsLow-dose normal stress-only WBR MPS has a reliable long-term prognostic value in patients with suspected or known CAD. This finding supports the introduction of such a method into clinical practice with a consistent dose optimization in the interest of patients and exposed staff.
ConclusionsIn nearly half of our patients, one or more normal myocardial segments showed absent or significantly reduced FDG uptake. This finding, particularly if it is diffuse, could be from suboptimal study, inadequacy of current glucose and insulin loading protocols, or various other patient-related causes affecting FDG uptake both in the normal and hibernating myocardium. In cases with significantly reduced FDG uptake in normal myocardium, PET images should be interpreted cautiously to prevent false-negative results for viability.
We report a case of hypercalcemia with normal PTH levels due to a parathyroid adenoma. Patient concerns: A 52-year-old female patient presented with 2-year history of documented sustained high-normal serum calcium and hypercalcemia (2.51–3.03 mmol/L) with normal serum intact PTH levels (21.95–40.15 pg/ mL). Diagnoses: A parathyroid tumor was localized by ultrasonography and 99mTc-sestamibi dual-phase fusion imaging with single-photon emission computed tomography/computed tomography. Interventions: Parathyroidectomy was performed to excise the tumor completely. Outcomes: A 1.2-cm-sized parathyroi...