Cognitive Impairment Associated with Cancer: A Brief Review
CONCLUSION Cognitive impairment can affect daily functioning, quality of life, and capacity to work in patients with cancer and those in remission. Consequently, cognitive assessment is now an important and necessary part of a comprehensive oncological care plan. Cancer-related cognitive impairment might be due to the direct effects of the cancer itself, nonspecific factors, or comorbid conditions that are independent of the disease and/or due to the adverse effects of the treatment or combination of treatments given for the disease. The prevalence and extent of cognitive impairment associated with cancer is recognized but not well understood due, in part, to marked differences in the research methods and definitions used for evaluating cognitive functioning in these patients. Most studies have identified attention, memory, and information processing as the most frequent cognitive domains impacted by cancer and cancer-related treatments, but further research clearly is needed. Recent efforts have been made to develop common definitions to define cognitive impairment in cancer patients and to suggest guidelines for the most appropriate cognitive tests to be used. Cognitive function has increasingly been recognized as a requisite therapeutic target in many diseases, including cancer. The extent of cognitive impairment that is observed in patients with cancer and those in remission make cognitive functioning a particularly important target for clinical trials and clinical practi...
Authors: Zhao J, Guo N, Zhang L, Wang L Abstract INTRODUCTION: CA125 has poor sensitivity and low specificity for detecting early ovarian cancer. Serum ferritin is elevated in many malignancies. We evaluated the performance of ferritin alone and in combination with CA125 as a diagnostic tool to detect epithelial ovarian cancer (EOC). METHODS: CA125 and ferritin were detected in the serum of 50 healthy control (HC), 50 women with benign gynaecological conditions and 124 women with EOC. The relationship between serum ferritin and CA125 and each of the clinicopathological parameters was assessed, and their diagnos...
KEEPING fit in older age helps stave off Alzheimer ’s disease, according to research. Scientists have discovered that bursts of exercise, such as a bike ride or a brisk walk, boost “white matter” tissue found deep within the brain.
Hundreds of hardy Penn State students have raised more than $10 million for pediatric cancer patients in the annual 46-hour dance marathon known as Thon
Authors: Gupta B, Patel A, Kar SK PMID: 29453144 [PubMed - as supplied by publisher]
CONCLUSIONS: Despite feeling that they require mental health services, few trainees actually sought care. This study identifies an overall need for improved access to mental health providers and psychoeducation for medical housestaff. PMID: 29450842 [PubMed - as supplied by publisher]
CONCLUSIONS: Both rural men and rural women report more barriers to help seeking for mental health issues than physical health issues across a range of domains. There is a need to educate the current and future rural health and mental health workforce about these barriers and to encourage them to test evidence-based strategies to address them, in particular to facilitate more widespread mental health help-seeking in rural Australia. PMID: 29451985 [PubMed - in process]
Authors: Petrou P Abstract INTRODUCTION: The therapeutic categories of Tyrosine Kinase Inhibitors of Vascular Endothelial Growth Factor Receptors, mammalian target of rapamycin inhibitors and Programmed Death-1 inhibitors have transformed the treatment of metastatic renal cell cancer. Nevertheless, this comes at an increased cost, in tandem with similar fiscal pressures in the broader oncology sector, which may jeopardize the sustainability of health systems. Areas covered To this direction, the economic evaluation of these agents is essential for rational and efficient resource allocation. The aim of this study is...
Thread Starter Oncogenes explained? Follow 2 minutes ago 2m ago Quote: Originally Posted by MedStudentt Does anyone know any good sites that explain the molecular biology underpining oncogenes especially TP53 and Rb? Specifically in relation to HPV virus and cervica...
ConclusionThese results suggest that increasing physical activity may be an effective strategy for improving the quality of sleep in girls during early adolescence.This article is protected by copyright. All rights reserved.
CONCLUSIONS: Since the onset of the economic crisis in Spain the rate of decline in cancer mortality has slowed significantly, and this situation could be exacerbated by the current austerity measures in healthcare. PMID: 29452751 [PubMed - as supplied by publisher]
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