GSE106960 The single cell RNA seq of pulmonary alveolar epithelial cells

Contributors : Yanjie Wang ; Nan Tang ; Tao CaiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe pulmonary alveolar epithelium which play key role in lung biological function is mainly composed of two types of epithelial cells: alveolar type I (AT1) and type II (AT2) cells. We know very little about developmental heterogeneity of the AT1 cell population. By using 10X genomics “Chromium Single Cell” technology, we performed single-cell RNA-seq (scRNA-seq) analyses of AT1 cells at postnatal day 3 (P3), P15, and P60, along with AT2 cells (P60) in mice. Our study identified a robust new genetic marker (Igfbp2) of postnatal AT1 cells. The study also provided the transcrip tome information of AT1 cells during alveologensis.

Source: GEO: Gene Expression Omnibus - February 5, 2018 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research