Characterization of the stimulus waveforms generated by implantable pulse generators for deep brain stimulation

Deep brain stimulation (DBS) is an established therapy to treat several neurological disorders (e.g. essential tremor, Parkinson ’s disease, dystonia, obsessive-compulsive disorder) (Benabid et al., 1991; Greenberg et al., 2010; Obeso et al., 2001; Vidailhet et al., 2005) and its efficacy is being explored for a range of additional indications (e.g. epilepsy, treatment-resistant depression, neuropathic pain, Tourette syndro me) (Fisher et al., 2010; Holtzheimer, 2012; Lempka et al., 2017; Malone et al., 2009; Morrell and RNS System in Epilepsy Study Group, 2011; Schrock et al., 2015).

Source: Clinical Neurophysiology - February 4, 2018 Category: Neuroscience Authors: Scott F. Lempka, Bryan Howell, Kabilar Gunalan, Andre G. Machado, Cameron C. McIntyre Source Type: research