Historical perspectives on tardive dyskinesia

Tardive dyskinesia (TD) is a persistent hyperkinetic movement disorder associated with dopamine receptor blocking agents including antipsychotic medications. Although uncertainty and concern about this drug side effect has vacillated since its initial recognition 60  years ago, recent commercial interest in developing effective treatments has rekindled scientific and clinical interest after a protracted period of neglect. Although substantial research has advanced knowledge of the clinical features and epidemiology of TD, many fundamental questions raised by early investigators remain unresolved.

Source: Journal of the Neurological Sciences - February 3, 2018 Category: Neurology Authors: Stanley N. Caroff, Gabor S. Ungvari, David G. Cunningham Owens Tags: Review Article Source Type: research