Pituitary gland shrinkage in bipolar disorder: The role of gender

Hyperactivity of the Hypothalamic-Pituitary-Adrenal Axis (HPAA) has been consistently reported in mood disorders. However, only few studies investigated the Pituitary gland (PG) in Bipolar Disorder (BD) and the results are so far contrasting. Therefore, the aim of this study is to explore the integrity of the PG as well as the role of gender and the impact of clinical measurements on this structure in a sample of BD patients compared to healthy controls (HC).

Source: Comprehensive Psychiatry - February 3, 2018 Category: Psychiatry Authors: Giuseppe Delvecchio, Gian Mario Mandolini, Cinzia Perlini, Marco Barillari, Veronica Marinelli, Mirella Ruggeri, A. Carlo Altamura, Marcella Bellani, Paolo Brambilla Source Type: research