Abnormal NHC supported palladacycles: Regioselective arylation of heteroarenes via decarboxylation

We report synthesis of two new palladium(II) complexes of abnormal N-heterocyclic carbene ligands. The catalytic activity of these palladium(II) complexes was examined for the decarboxylative arylation of N-methylindole-carboxylic acids. An exclusive regioselectivity and very good yields were obtained with a variety of aryl halide partners. Graphical abstract

Source: Journal of Organometallic Chemistry - February 3, 2018 Category: Chemistry Source Type: research